Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.56 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1466284 | 0.85 | PTGDR2 (0.77) | PTGDR2PTGDRPTGIR | |
| SCHEMBL1466741 | 0.85 | PTGDR2 (0.66) | PTGDR2PTGDRPTGIR | |
| SCHEMBL3722473 | 0.81 | PTGDR2 (0.72) | PTGDR2PTGDRPTGIR | |
| SCHEMBL1921222 | 0.81 | PTGDR2 (0.41) | PTGDR2 | |
| SCHEMBL3717896 | 0.79 | PTGDR2 (0.60) | PTGDR2PTGDRPTGIR | |
| SCHEMBL1466930 | 0.77 | PTGDR2 (0.73) | PTGDR2PTGDRPTGIR | |
| SCHEMBL1465346 | 0.76 | PTGDR2 (0.62) | PTGDR2PTGDRPTGIR | |
| SCHEMBL2977551 | 0.75 | PLA2G4A (0.44) | PTGDR2 | |
| SCHEMBL27799170 | 0.73 | PTGDR2 (0.68) | PTGDR2PTGDR | |
| SCHEMBL27799169 | 0.73 | PTGDR2 (0.76) | PTGDR2PTGDRPTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2327693-A1 | Indoles and their therapeutic use | Pulmagen Therapeutics (Asthma) Limited (GB) | 2011-06-01 | — | — | EP | disclosed |