Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 15/20 | 0.62 |
| ▸ | ACACA | Q13085 | 13/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13076817 | 0.93 | ACACB (0.53) | ACACBACACACYP2C9CYP3A4 | |
| SCHEMBL3806064 | 0.89 | ACACB (0.49) | ACACBACACACYP2C9CYP3A4 | |
| SCHEMBL3723075 | 0.88 | ACACB (0.57) | ACACBACACACYP2C9CYP3A4 | |
| SCHEMBL3720196 | 0.88 | ACACA (0.61) | ACACBACACA | |
| SCHEMBL3720062 | 0.88 | ACACB (0.49) | ACACBACACACYP2C9CYP3A4 | |
| SCHEMBL13077088 | 0.87 | ACACB (0.51) | ACACBACACA | |
| SCHEMBL3721287 | 0.86 | ACACA (0.51) | ACACBACACACYP2C9CYP3A4 | |
| SCHEMBL3720493 | 0.86 | ACACA (0.50) | ACACBACACACYP2C9CYP3A4 | |
| SCHEMBL3726987 | 0.85 | ACACB (0.48) | ACACBACACACYP2C9CYP3A4 | |
| SCHEMBL3724181 | 0.84 | ACACA (0.52) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |