⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL372314 | 0.85 | — | — | |
| SCHEMBL29025516 | 0.75 | — | — | |
| SCHEMBL28991351 | 0.73 | — | — | |
| SCHEMBL10593884 | 0.73 | — | — | |
| SCHEMBL674162 | 0.69 | — | — | |
| SCHEMBL10575183 | 0.67 | — | — | |
| SCHEMBL2458962 | 0.67 | — | — | |
| Ethylene SCHEMBL19987895 | 0.65 | — | — | |
| SCHEMBL243362 | 0.65 | — | — | |
| SCHEMBL76624 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1197870-C | Preparation method and intermediate of erythromycin derivative | TAISHO PHARMACEUTICAL CO LTD (JP) | 2005-04-20 | — | — | CN | claimed |
| US-6713615-B2 | Process for producing erythromycin derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2004-03-30 | — | — | US | claimed |
| US-20030191295-A1 | Process for producing erythromycin derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2003-10-09 | — | — | US | claimed |
| CN-1446224-A | Process for producing erythromycin derivative | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-10-01 | — | — | CN | claimed |
| EP-1310506-A1 | PROCESS FOR PRODUCING ERYTHROMYCIN DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2003-05-14 | — | — | EP | claimed |
| EP-2261212-B1 | Preparation of quinoline-substituted carbamate derivatives | ABBVIE INC (US) | 2016-08-31 | — | — | EP | disclosed |
| EP-2409964-B1 | Process for the preparation of carbonate derivatives | ABBOTT LAB (US) | 2016-01-27 | — | — | EP | disclosed |
| EP-1192139-B1 | Preparation of quinoline-substituted carbonate and carbamate derivatives | ABBOTT LAB (US) | 2012-04-18 | — | — | EP | disclosed |
| EP-2409964-A2 | Preparation of substituted carbonate and carbamate derivatives | Abbott Laboratories (US) | 2012-01-25 | — | — | EP | disclosed |
| EP-2261212-A2 | Preparation of quinoline-substituted carbonate and carbamate derivatives | Abbott Laboratories (US) | 2010-12-15 | — | — | EP | disclosed |
| US-7074932-B2 | Preparation of quinoline-substituted carbonate and carbamate derivatives | ABBVIE INC. | 2006-07-11 | — | — | US | disclosed |
| US-20060128962-A1 | Preparation of quinoline-substituted carbonate and carbamate derivatives | ALLEN MICHAEL S | 2006-06-15 | — | — | US | disclosed |
| CN-1446224-A | Process for producing erythromycin derivative | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-10-01 | — | — | CN | disclosed |
| US-6579986-B2 | Metal-catalyzed coupling reactions for 6-o-substituted macrolide antibiotics | ABBOTT LABORATORIES | 2003-06-17 | — | — | US | disclosed |
| EP-1310506-A1 | PROCESS FOR PRODUCING ERYTHROMYCIN DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-20020165390-A1 | Preparation of quinoline-substituted carbonate and carbamate derivatives | ABBVIE INC. | 2002-11-07 | — | — | US | disclosed |
| US-6417366-B2 | CHEMICAL INTERMEDIATE FOR MACROLACTONE ANTIBIOTIC | ABBOTT LABORATORIES | 2002-07-09 | — | — | US | disclosed |
| EP-1192139-A1 | PREPARATION OF QUINOLINE-SUBSTITUTED CARBONATE AND CARBAMATE DERIVATIVES | Abbott Laboratories (US) | 2002-04-03 | — | — | EP | disclosed |
| US-20020013468-A1 | Preparation of quinoline-substituted carbonate and carbamate derivatives | ABBVIE INC. | 2002-01-31 | — | — | US | disclosed |
| WO-2001000582-A1 | PREPARATION OF QUINOLINE-SUBSTITUTED CARBONATE AND CARBAMATE DERIVATIVES | ABBOTT LABORATORIES (US) | 2001-01-04 | — | — | WO | disclosed |