Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6224120 | 0.83 | PARP10 (0.44) | PTGS1PTGS2PARP10TSHRPDK2 | |
| SCHEMBL1049033 | 0.81 | PDK2 (0.44) | HPGDPTGS1PTGS2PARP10TSHR | |
| SCHEMBL34474819 | 0.79 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HPGDHRH3 | |
| SCHEMBL3721762 | 0.79 | PTGS1 (0.44) | HRH3PTGS1PTGS2PARP10TSHR | |
| SCHEMBL12476213 | 0.79 | PTGS1 (0.41) | PTGS1PTGS2PARP10TSHRPDK2 | |
| SCHEMBL25956126 | 0.79 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HPGDHRH3 | |
| SCHEMBL3416691 | 0.78 | MAOB (0.54) | HPGDHRH3PTGS1PTGS2PARP10 | |
| SCHEMBL15100422 | 0.78 | HSD11B1 (0.40) | SLC6A2SLC6A4SLC6A3TSHRHSD17B10 | |
| SCHEMBL7172082 | 0.78 | HSD11B1 (0.40) | SLC6A2SLC6A4SLC6A3TSHRHSD17B10 | |
| SCHEMBL15100425 | 0.78 | HSD11B1 (0.40) | SLC6A2SLC6A4SLC6A3TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012090219-A2 | THIAZOLE COMPOUNDS USEFUL AS ACETYL-COA CARBOXYLASE (ACC) INHIBITORS | JUBILANT BIOSYS LTD. (IN) | 2012-07-05 | — | — | WO | disclosed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |