Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 3/20 | 0.36 |
| ▸ | ESRRG | P62508 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3729093 | 0.83 | F2R (0.39) | SMN1; SMN2S1PR1S1PR5S1PR3S1PR4 | |
| SCHEMBL23932469 | 0.82 | AKR1C3 (0.57) | AKR1C3AKR1C1KAT2B | |
| SCHEMBL3723289 | 0.82 | F2R (0.46) | S1PR1S1PR5S1PR3S1PR4AKR1C3 | |
| SCHEMBL1580970 | 0.78 | NOTUM (0.47) | AKR1C3AKR1C1F2R | |
| SCHEMBL3723291 | 0.74 | FFAR4 (0.36) | PPARA | |
| SCHEMBL10618142 | 0.73 | AKR1C3 (0.45) | S1PR1S1PR5S1PR3S1PR4AKR1C3 | |
| SCHEMBL3770314 | 0.73 | F2R (0.43) | SMN1; SMN2F2RCYP4F2CYP4A11 | |
| SCHEMBL15498535 | 0.71 | LSS (0.55) | ESRRG | |
| SCHEMBL22071093 | 0.70 | CYP4F2 (0.55) | SMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL14140480 | 0.70 | CYP4F2 (0.46) | SMN1; SMN2AKR1C3AKR1C1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136138-A1 | SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-12-02 | — | — | WO | disclosed |