Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1054892 | 0.85 | F2R (0.44) | F2RAKR1C3AKR1C1S1PR1S1PR5 | |
| SCHEMBL3723285 | 0.83 | SMN1; SMN2 (0.41) | F2RSMN1; SMN2AKR1C3AKR1C1S1PR1 | |
| SCHEMBL1580970 | 0.83 | NOTUM (0.47) | F2RAKR1C3AKR1C1 | |
| SCHEMBL3720678 | 0.82 | HRH3 (0.41) | S1PR1S1PR5 | |
| SCHEMBL1053602 | 0.80 | RORC (0.44) | F2R | |
| SCHEMBL23932469 | 0.79 | AKR1C3 (0.57) | AKR1C3AKR1C1CHRM4 | |
| SCHEMBL1050074 | 0.77 | F2R (0.52) | F2R | |
| SCHEMBL1056589 | 0.77 | F2R (0.41) | F2R | |
| SCHEMBL3724546 | 0.75 | KDM1A (0.47) | — | |
| SCHEMBL21381673 | 0.74 | ALDH1A1 (0.38) | F2RSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136138-A1 | SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-12-02 | — | — | WO | disclosed |
| WO-2010136144-A1 | SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-12-02 | — | — | WO | disclosed |