Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | VNN1 | O95497 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.46 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772477 | 0.85 | FFAR1 (0.53) | FFAR1FFAR4MAOBLMNAPTGDR2 | |
| SCHEMBL6668868 | 0.83 | MRGPRX4 (0.55) | FFAR1FFAR4MAOBMRGPRX4MEP1A | |
| SCHEMBL21885801 | 0.82 | FFAR1 (0.61) | FFAR1FFAR4MAOBLMNAMRGPRX4 | |
| SCHEMBL31568453 | 0.82 | TSHR (0.56) | FFAR1FFAR4MAOBLMNAMRGPRX4 | |
| SCHEMBL22469683 | 0.82 | TSHR (0.56) | FFAR1FFAR4MAOBLMNAMRGPRX4 | |
| SCHEMBL3722688 | 0.80 | HTT (0.51) | FFAR4MAOBPTGDR2SMN1; SMN2 | |
| SCHEMBL20551473 | 0.80 | MRGPRX4 (0.53) | FFAR1FFAR4MAOBMRGPRX4KCNH2 | |
| SCHEMBL5038094 | 0.78 | CTBP2 (0.47) | FFAR1 | |
| SCHEMBL335418 | 0.78 | LMNA (0.56) | FFAR1FFAR4LMNAVNN1FOLH1 | |
| SCHEMBL2774422 | 0.78 | FFAR1 (0.48) | FFAR1FFAR4MAOBMRGPRX4VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414341-B1 | OXADIAZOLE DERIVATIVES | MERCK SERONO SA (CH) | 2017-09-13 | — | — | EP | disclosed |
| US-8815919-B2 | Oxadiazole derivatives | MERCK SERONO SA (CH) | 2014-08-26 | — | — | US | disclosed |
| WO-2010115751-A2 | OXADIAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2010-10-14 | — | — | WO | disclosed |