Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.50 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16360403 | 0.92 | CYP2D6 (0.52) | ACE2LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL11077957 | 0.92 | CYP2D6 (0.52) | ACE2LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL11397604 | 0.85 | ACE2 (0.52) | ACE2LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL6722464 | 0.84 | CYP2D6 (0.56) | ACE2LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL27634084 | 0.83 | ACE2 (0.50) | ACE2LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL19519901 | 0.82 | ACE2 (0.48) | ACE2LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL19520052 | 0.82 | ACE2 (0.48) | ACE2LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9555606 | 0.81 | ACE2 (0.47) | ACE2LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9555604 | 0.81 | ACE2 (0.47) | ACE2LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL21220026 | 0.80 | ACE2 (0.47) | ACE2LCKPPARDZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393809-A2 | DERIVATIVES OF AZASPIRANYL-ALKYLCARBAMATES OF 5-MEMBER HETEROCYCLIC COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010089510-A2 | DERIVATIVES OF AZASPIRANYL-ALKYLCARBAMATES OF 5-MEMBER HETEROCYCLIC COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-08-12 | — | — | WO | disclosed |