Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | ZDHHC7 | Q9NXF8 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.40 |
| ▸ | ADH1C | P00326 | 1/20 | 0.40 |
| ▸ | ADH1A | P07327 | 1/20 | 0.40 |
| ▸ | ADH4 | P08319 | 1/20 | 0.40 |
| ▸ | ADH7 | P40394 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19519901 | 0.98 | ACE2 (0.48) | ACE2ZDHHC7LCKPPARDZDHHC20 | |
| SCHEMBL19520052 | 0.98 | ACE2 (0.48) | ACE2ZDHHC7LCKPPARDZDHHC20 | |
| SCHEMBL18085370 | 0.92 | ACE2 (0.41) | ACE2ZDHHC7EPHX1CA1MAPK1 | |
| SCHEMBL19519903 | 0.92 | ACE2 (0.41) | ACE2ZDHHC7EPHX1CA1MAPK1 | |
| SCHEMBL10112804 | 0.92 | ACE2 (0.41) | ACE2ZDHHC7EPHX1CA1MAPK1 | |
| SCHEMBL3723458 | 0.85 | ACE2 (0.56) | ACE2LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL8436494 | 0.84 | TSHR (0.42) | ZDHHC7EPHX1MAPK1 | |
| SCHEMBL27634084 | 0.83 | ACE2 (0.50) | ACE2ZDHHC7LCKPPARDZDHHC20 | |
| SCHEMBL15697915 | 0.83 | KDM4E (0.59) | ACE2ZDHHC7EPHX1SIRT6SIRT1 | |
| SCHEMBL22591738 | 0.82 | LMNA (0.48) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243681-A | VASODILATION, ANTISPASMODIC AGENTS; ANTICOAGULANTS | MEAD JOHNSON & COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4147805-A | VASODILATION, ANTISPASMODIC AGENTS, ANTICOAGULATNS, ADRENOLYTIC AGENTS | MEAD JOHNSON & COMPANY (US) | 1979-04-03 | — | — | US | disclosed |