Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716329 | 0.81 | HTR2A (0.48) | HTR2AL3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL3720960 | 0.78 | KDM4E (0.37) | HTR2ACYP1A2ALDH1A1KDM4EERBB2 | |
| SCHEMBL9445712 | 0.76 | HTR2A (0.65) | HTR2AL3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL1136454 | 0.76 | HTR2A (0.50) | HTR2AL3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL714592 | 0.75 | CYP1A2 (0.46) | MEN1KMT2ACYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL29825535 | 0.75 | CYP1A2 (0.46) | MEN1KMT2ACYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL3718356 | 0.74 | CYP1A2 (0.42) | CYP1A2HIF1A | |
| SCHEMBL16414524 | 0.72 | HTR2A (0.56) | HTR2AL3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL29039909 | 0.72 | CYP1A2 (0.38) | MEN1KMT2ACYP1A2HSD17B10ALDH1A1 | |
| SCHEMBL7877776 | 0.72 | HTR2A (0.60) | HTR2AL3MBTL1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010112946-A1 | ADAMANTANE BISUREA DERIVATIVES, METHOD OF PREPARATION AND APPLICATION IN ANION SENSING | RUDJER BOSKOVIC INSTITUTE (HR) | 2010-10-07 | — | — | WO | claimed |
| WO-2010112946-A1 | ADAMANTANE BISUREA DERIVATIVES, METHOD OF PREPARATION AND APPLICATION IN ANION SENSING | RUDJER BOSKOVIC INSTITUTE (HR) | 2010-10-07 | — | — | WO | disclosed |