Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BID | P55957 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30140890 | 0.84 | CA2 (0.49) | CA2SMN1; SMN2CA1CA9CA12 | |
| SCHEMBL51728 | 0.84 | CA2 (0.49) | CA2SMN1; SMN2CA1CA9CA12 | |
| SCHEMBL18989503 | 0.83 | CA2 (0.45) | CA2SMN1; SMN2BIDMCL1BCL2L1 | |
| SCHEMBL3278456 | 0.83 | CA2 (0.45) | CA2SMN1; SMN2BIDMCL1BCL2L1 | |
| SCHEMBL6062879 | 0.83 | CA2 (0.45) | CA2SMN1; SMN2BIDMCL1BCL2L1 | |
| Ammonia Solution, Strong SCHEMBL28168503 | 0.83 | CA2 (0.47) | CA2SMN1; SMN2CA1CA9CA12 | |
| SCHEMBL7444688 | 0.83 | CA2 (0.47) | CA2SMN1; SMN2CA1CA9CA12 | |
| Methane SCHEMBL27933205 | 0.83 | CA2 (0.47) | CA2SMN1; SMN2CA1CA9CA12 | |
| SCHEMBL3978112 | 0.82 | CA2 (0.44) | CA2SMN1; SMN2BIDMCL1BCL2L1 | |
| SCHEMBL7261112 | 0.82 | CA2 (0.44) | CA2SMN1; SMN2BIDMCL1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132016-A1 | BIS-(SULFONYLAMINO) DERIVATIVES FOR TREATMENT OF PAIN AND INFLAMMATION | ASTRAZENECA AB (SE) | 2010-11-18 | — | — | WO | disclosed |