Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | CA12 | O43570 | 3/20 | 0.61 |
| ▸ | CA9 | Q16790 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | SCN1A | P35498 | 2/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229994 | 0.83 | RECQL (0.88) | RECQLCA12CA9ALDH1A1TSHR | |
| SCHEMBL9738489 | 0.83 | CA12 (0.66) | RECQLCA12CA9ALDH1A1TSHR | |
| SCHEMBL18989501 | 0.83 | CA9 (0.61) | RECQLCA12CA9ALDH1A1TSHR | |
| SCHEMBL31391062 | 0.81 | CA12 (0.63) | RECQLCA12CA9ALDH1A1TSHR | |
| SCHEMBL9462811 | 0.81 | CA12 (0.63) | RECQLCA12CA9ALDH1A1TSHR | |
| SCHEMBL635553 | 0.81 | CA12 (0.63) | RECQLCA12CA9ALDH1A1TSHR | |
| SCHEMBL9738480 | 0.81 | CA12 (0.63) | RECQLCA12CA9ALDH1A1TSHR | |
| SCHEMBL13296442 | 0.80 | CYP3A4 (0.65) | RECQLCA12CA9ALDH1A1TSHR | |
| SCHEMBL3978111 | 0.80 | CA12 (0.61) | RECQLCA12CA9ALDH1A1TSHR | |
| SCHEMBL7111715 | 0.79 | CA12 (0.67) | RECQLCA12CA9ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132016-A1 | BIS-(SULFONYLAMINO) DERIVATIVES FOR TREATMENT OF PAIN AND INFLAMMATION | ASTRAZENECA AB (SE) | 2010-11-18 | — | — | WO | disclosed |