Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722166 | 0.85 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL3722717 | 0.82 | P2RX7 (0.71) | P2RX7 | |
| SCHEMBL3726337 | 0.80 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL3729822 | 0.70 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL3722998 | 0.70 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL3724803 | 0.69 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL3722621 | 0.68 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL3724531 | 0.67 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL3723247 | 0.67 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL3721127 | 0.67 | P2RX7 (1.00) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010125103-A1 | DIKETOPIPERAZINE DERIVATIVES AS P2X7 MODULATORS | GLAXO GROUP LIMITED (GB) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010125103-A1 | DIKETOPIPERAZINE DERIVATIVES AS P2X7 MODULATORS | GLAXO GROUP LIMITED (GB) | 2010-11-04 | — | — | WO | disclosed |