Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724327 | 0.90 | MTNR1A (0.58) | ACACBMTNR1AMTNR1BALDH1A1SCN9A | |
| SCHEMBL3722807 | 0.88 | MTNR1A (0.49) | ACACBMTNR1AMTNR1BALDH1A1SCN9A | |
| SCHEMBL3720900 | 0.88 | MTNR1A (0.51) | ACACBMTNR1AMTNR1BALDH1A1SCN9A | |
| SCHEMBL3726202 | 0.87 | ACACB (0.58) | ACACBMTNR1AMTNR1BALDH1A1SCN9A | |
| SCHEMBL3716841 | 0.87 | MTNR1A (0.54) | ACACBMTNR1AMTNR1BALDH1A1SCN9A | |
| SCHEMBL3727674 | 0.86 | MTNR1A (0.58) | ACACBMTNR1AMTNR1BALDH1A1SCN9A | |
| SCHEMBL3717149 | 0.86 | MTNR1A (0.58) | ACACBMTNR1AMTNR1BALDH1A1SCN9A | |
| SCHEMBL3727682 | 0.85 | MTNR1A (0.55) | ACACBMTNR1AMTNR1BSCN9A | |
| SCHEMBL3724569 | 0.85 | MTNR1A (0.55) | ACACBMTNR1AMTNR1BALDH1A1SCN9A | |
| SCHEMBL3727573 | 0.85 | MTNR1A (0.57) | ACACBMTNR1AMTNR1BALDH1A1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |