Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL612830 | 0.96 | MET (0.69) | METCYP3A4 | |
| SCHEMBL3722790 | 0.87 | MET (0.68) | METCYP3A4 | |
| SCHEMBL3719030 | 0.85 | MET (0.70) | METCYP3A4 | |
| SCHEMBL3719705 | 0.84 | MET (0.66) | METCYP3A4 | |
| SCHEMBL3723202 | 0.84 | MET (0.65) | METCYP3A4 | |
| SCHEMBL3723204 | 0.84 | MET (0.65) | METCYP3A4 | |
| SCHEMBL3406870 | 0.83 | MET (0.64) | METCYP3A4 | |
| SCHEMBL612424 | 0.83 | MET (0.70) | METCYP3A4 | |
| SCHEMBL3724257 | 0.83 | MET (0.70) | METCYP3A4 | |
| SCHEMBL612337 | 0.83 | MET (0.74) | METCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393790-A1 | DERIVATIVES OF 6-(6-O-CYCLOALKYL OR 6-NH-CYCLOALKYL-TRIAZOLOPYRIDAZINE-SULFANYL) BENZOTHIAZOLES AND BENZIMIDAZOLES, PREPARATION THEREOF, USE THEREOF AS DRUGS, AND USE THEREOF AS MET INHIBITORS | SANOFI (FR) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010089506-A1 | DERIVATIVES OF 6-(6-O-CYCLOALKYL OR 6-NH-CYCLOALKYL-TRIAZOLOPYRIDAZINE-SULFANYL) BENZOTHIAZOLES AND BENZIMIDAZOLES, PREPARATION THEREOF, USE THEREOF AS DRUGS, AND USE THEREOF AS MET INHIBITORS | SANOFI-AVENTIS (FR) | 2010-08-12 | — | — | WO | disclosed |