Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.59 |
| ▸ | KMO | O15229 | 8/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.44 |
| ▸ | PDE4A | P27815 | 4/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724558 | 0.98 | CSNK2A1 (0.58) | CSNK2A1KMORORCHPGDPDE4D | |
| SCHEMBL17253047 | 0.93 | RORC (0.54) | CSNK2A1KMORORCHPGDPDE4D | |
| SCHEMBL22816048 | 0.86 | CSNK2A1 (0.47) | CSNK2A1KMORORCPDE4DPDE4A | |
| SCHEMBL22816167 | 0.84 | CSNK2A1 (0.46) | CSNK2A1KMOHPGDPDE4DPDE4A | |
| SCHEMBL22815971 | 0.82 | CSNK2A1 (0.44) | CSNK2A1KMORORCPDE4DPDE4A | |
| SCHEMBL3723725 | 0.79 | CSNK2A1 (0.41) | CSNK2A1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL13349984 | 0.79 | CSNK2A1 (0.64) | CSNK2A1KMORORCHPGDPDE4D | |
| SCHEMBL12908030 | 0.79 | CSNK2A1 (0.59) | CSNK2A1KMORORCHPGDPDE4D | |
| SCHEMBL2419182 | 0.79 | CSNK2A1 (0.59) | CSNK2A1KMORORCHPGD | |
| SCHEMBL27478491 | 0.79 | CSNK2A1 (0.59) | CSNK2A1KMORORCHPGDSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |