Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721861 | 0.83 | PDE4B (0.53) | PDE4BALDH1A1MAPTGAANPC1 | |
| SCHEMBL3720024 | 0.83 | PDE4B (0.53) | PDE4BALDH1A1MAPTGAANPC1 | |
| SCHEMBL3717735 | 0.81 | PDE4B (0.57) | PDE4BALDH1A1MAPTGAASCD | |
| SCHEMBL13076364 | 0.80 | ACACB (0.50) | — | |
| SCHEMBL3722547 | 0.80 | PDE4B (0.52) | PDE4BMAPTNPC1RAB9AKMT2A | |
| SCHEMBL3724294 | 0.79 | PDE4B (0.55) | PDE4BALDH1A1MAPTGAARAB9A | |
| SCHEMBL3723898 | 0.78 | PDE4B (0.50) | PDE4BMAPTGAANPC1RAB9A | |
| SCHEMBL3721431 | 0.78 | PDE4B (0.53) | PDE4BALDH1A1LMNAGLAAKR1C3 | |
| SCHEMBL3718630 | 0.78 | PDE4B (0.54) | PDE4BALDH1A1MAPT | |
| SCHEMBL3717019 | 0.78 | CYP1A2 (0.43) | ALDH1A1MAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |