Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 16/20 | 0.56 |
| ▸ | ACACA | Q13085 | 10/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721078 | 0.88 | ACACB (0.49) | ACACBACACALMNAALOX5 | |
| SCHEMBL13077068 | 0.87 | ACACB (0.56) | ACACBACACALMNAAKR1C3AKR1C2 | |
| SCHEMBL13077240 | 0.86 | ACACB (0.56) | ACACBACACAALOX5 | |
| SCHEMBL3726815 | 0.86 | ACACB (0.74) | ACACBACACAAKR1C3AKR1C2 | |
| SCHEMBL13077238 | 0.84 | ACACB (0.53) | ACACBACACALMNAALOX5AKR1C3 | |
| SCHEMBL3720746 | 0.83 | ACACB (0.52) | ACACBACACALMNAAKR1C3AKR1C2 | |
| SCHEMBL3720304 | 0.83 | ACACB (0.79) | ACACBACACAAKR1C3AKR1C2 | |
| SCHEMBL13076810 | 0.82 | ACACB (0.58) | ACACBACACALMNAAKR1C3AKR1C2 | |
| SCHEMBL3722995 | 0.82 | ACACB (0.49) | ACACBACACALMNAAKR1C3AKR1C2 | |
| SCHEMBL3726745 | 0.81 | ACACB (0.57) | ACACBACACALMNAAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |