Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 18/20 | 0.52 |
| ▸ | ACACA | Q13085 | 10/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719222 | 0.87 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL13077046 | 0.84 | ACACB (0.54) | ACACBACACA | |
| SCHEMBL3724675 | 0.83 | ACACB (0.56) | ACACBACACAAKR1C3AKR1C2LMNA | |
| SCHEMBL13077068 | 0.83 | ACACB (0.56) | ACACBACACAAKR1C3AKR1C2LMNA | |
| SCHEMBL3726815 | 0.82 | ACACB (0.74) | ACACBACACAAKR1C3AKR1C2 | |
| SCHEMBL13077087 | 0.81 | ACACB (0.48) | ACACBACACA | |
| SCHEMBL13077238 | 0.81 | ACACB (0.53) | ACACBACACAAKR1C3AKR1C2LMNA | |
| SCHEMBL3719867 | 0.81 | ACACA (0.60) | ACACBACACA | |
| SCHEMBL3722464 | 0.80 | CYP17A1 (0.41) | ACACBACACA | |
| SCHEMBL3718429 | 0.80 | ACACB (0.44) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |