SCHEMBL372486

SCHEMBL372486

CCCCN[Si](OC)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
LMNA P02545 1/20 0.39
ALDH1A1 P00352 1/20 0.35
CA12 O43570 2/20 0.35
CA14 Q9ULX7 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
ADH1B P00325 1/20 0.35
ADH1C P00326 1/20 0.35
ADH1A P07327 1/20 0.35
ADH7 P40394 1/20 0.35
CA7 P43166 1/20 0.35
ACHE P22303 7/20 0.33
EPHX1 P07099 4/20 0.33
TLR8 Q9NR97 1/20 0.32
TLR7 Q9NYK1 1/20 0.32
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL372722 0.92 TSHR (0.46) TSHRLMNAALDH1A1CA12CA14
SCHEMBL371997 0.90 EPHX1 (0.46) TSHRLMNAALDH1A1CA12CA14
SCHEMBL6653908 0.90 EPHX1 (0.46) TSHRLMNAALDH1A1CA12CA14
SCHEMBL27535401 0.90 EPHX1 (0.46) TSHRLMNAALDH1A1CA12CA14
SCHEMBL372635 0.90 EPHX1 (0.46) TSHRLMNAALDH1A1CA12CA14
SCHEMBL372924 0.90 EPHX1 (0.46) TSHRLMNAALDH1A1CA12CA14
Bromide SCHEMBL27930800 0.87 EPHX1 (0.44) TSHRLMNAALDH1A1CA12CA14
SCHEMBL372475 0.86 CYP1A2 (0.30)
Hydrochloric Acid SCHEMBL10437282 0.83
SCHEMBL5799270 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11465570-B2 Extrusion grade perlite reinforced polypropylene polymer FORD GLOBAL TECHNOLOGIES, LLC (US) 2022-10-11 US claimed
US-20200198555-A1 EXTRUSION GRADE PERLITE REINFORCED POLYPROPYLENE POLYMER FORD GLOBAL TECHNOLOGIES, LLC (US) 2020-06-25 US claimed
US-10632936-B2 Extrusion grade perlite reinforced polypropylene polymer FORD GLOBAL TECHNOLOGIES, LLC (US) 2020-04-28 US claimed
US-20180326922-A1 EXTRUSION GRADE PERLITE REINFORCED POLYPROPYLENE POLYMER FORD GLOBAL TECHNOLOGIES, LLC (US) 2018-11-15 US claimed
CN-105849213-A Moisture curable compositions 道康宁公司 2016-08-10 CN claimed
US-9133281-B2 Preparation and use of functionalized elastomers in rubber compositions containing silica filler and tire components thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2015-09-15 US claimed
US-20140155542-A1 PREPARATION AND USE OF FUNCTIONALIZED ELASTOMERS IN RUBBER COMPOSITIONS CONTAINING SILICA FILLER AND TIRE COMPONENTS THEREOF THE GOODYEAR TIRE & RUBBER COMPANY (US) 2014-06-05 US claimed
US-8357747-B2 Polymer compositions comprising fluoro elastomers and expanded perlite IMERYS FILTRATION MINERALS, INC. (US) 2013-01-22 US claimed
EP-2410025-A1 Barrier compositions Imerys Minerals Limited (GB) 2012-01-25 EP claimed
US-20100317789-A1 Polymer Compositions Comprising Fluoro Elastomers and Expanded Perlite WORLD MINERALS, INC 2010-12-16 US claimed
US-20100105824-A1 Polymer Compositions WORLD MINERALS, INC. (US) 2010-04-29 US claimed
US-20090321681-A1 Barrier Compositions IMERYS MINERALS, LTD. (GB) 2009-12-31 US claimed
EP-2115057-A1 POLYMER COMPOSITIONS COMPRISING FLUORO ELASTOMERS AND EXPANDED PERLITE World Minerals, Inc. (US) 2009-11-11 EP claimed
EP-2016139-A2 BARRIER COMPOSITIONS Imerys Minerals Limited (GB) 2009-01-21 EP claimed
WO-2008081173-A1 POLYMER COMPOSITIONS COMPRISING FLUORO ELASTOMERS AND EXPANDED PERLITE WORLD MINERALS, INC. (US) 2008-07-10 WO claimed
WO-2008053236-A1 POLYMER COMPOSITIONS WORLD MINERALS, INC. (US) 2008-05-08 WO claimed
CN-101090876-A Particulate material IMERYS MINERALS LTD (GB) 2007-12-19 CN claimed
WO-2007125312-A2 BARRIER COMPOSITIONS IMERYS MINERALS LIMITED (GB) 2007-11-08 WO claimed
EP-1809581-A1 PARTICULATE MATERIAL Imerys Minerals Limited (GB) 2007-07-25 EP claimed
WO-2007010276-A1 PARTICULATE MATERIAL IMERYS MINERALS LIMITED (GB) 2007-01-25 WO claimed