SCHEMBL372722

SCHEMBL372722

CCCCCN[Si](OC)(OC)OC

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
ALDH1A1 P00352 1/20 0.46
EPHX1 P07099 8/20 0.42
ADH1B P00325 2/20 0.37
ADH1C P00326 2/20 0.37
ADH1A P07327 2/20 0.37
ADH7 P40394 2/20 0.37
ADH4 P08319 1/20 0.37
LMNA P02545 2/20 0.37
THRB P10828 1/20 0.35
PPARA Q07869 2/20 0.33
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
GBA1 P04062 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL372635 0.97 EPHX1 (0.46) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL371997 0.97 EPHX1 (0.46) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL6653908 0.97 EPHX1 (0.46) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL27535401 0.97 EPHX1 (0.46) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL372924 0.97 EPHX1 (0.46) TSHRALDH1A1EPHX1ADH1BADH1C
Bromide SCHEMBL27930800 0.95 EPHX1 (0.44) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL372486 0.92 TSHR (0.39) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL372475 0.83 CYP1A2 (0.30)
Hydrochloric Acid SCHEMBL10437282 0.81
SCHEMBL5799270 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11465570-B2 Extrusion grade perlite reinforced polypropylene polymer FORD GLOBAL TECHNOLOGIES, LLC (US) 2022-10-11 US claimed
US-20200198555-A1 EXTRUSION GRADE PERLITE REINFORCED POLYPROPYLENE POLYMER FORD GLOBAL TECHNOLOGIES, LLC (US) 2020-06-25 US claimed
US-10632936-B2 Extrusion grade perlite reinforced polypropylene polymer FORD GLOBAL TECHNOLOGIES, LLC (US) 2020-04-28 US claimed
US-20180326922-A1 EXTRUSION GRADE PERLITE REINFORCED POLYPROPYLENE POLYMER FORD GLOBAL TECHNOLOGIES, LLC (US) 2018-11-15 US claimed
US-9133281-B2 Preparation and use of functionalized elastomers in rubber compositions containing silica filler and tire components thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2015-09-15 US claimed
US-20140155542-A1 PREPARATION AND USE OF FUNCTIONALIZED ELASTOMERS IN RUBBER COMPOSITIONS CONTAINING SILICA FILLER AND TIRE COMPONENTS THEREOF THE GOODYEAR TIRE & RUBBER COMPANY (US) 2014-06-05 US claimed
US-8357747-B2 Polymer compositions comprising fluoro elastomers and expanded perlite IMERYS FILTRATION MINERALS, INC. (US) 2013-01-22 US claimed
EP-2410025-A1 Barrier compositions Imerys Minerals Limited (GB) 2012-01-25 EP claimed
US-20100317789-A1 Polymer Compositions Comprising Fluoro Elastomers and Expanded Perlite WORLD MINERALS, INC 2010-12-16 US claimed
US-20100105824-A1 Polymer Compositions WORLD MINERALS, INC. (US) 2010-04-29 US claimed
US-20090321681-A1 Barrier Compositions IMERYS MINERALS, LTD. (GB) 2009-12-31 US claimed
EP-2115057-A1 POLYMER COMPOSITIONS COMPRISING FLUORO ELASTOMERS AND EXPANDED PERLITE World Minerals, Inc. (US) 2009-11-11 EP claimed
EP-2016139-A2 BARRIER COMPOSITIONS Imerys Minerals Limited (GB) 2009-01-21 EP claimed
WO-2008081173-A1 POLYMER COMPOSITIONS COMPRISING FLUORO ELASTOMERS AND EXPANDED PERLITE WORLD MINERALS, INC. (US) 2008-07-10 WO claimed
WO-2008053236-A1 POLYMER COMPOSITIONS WORLD MINERALS, INC. (US) 2008-05-08 WO claimed
WO-2007125312-A2 BARRIER COMPOSITIONS IMERYS MINERALS LIMITED (GB) 2007-11-08 WO claimed
EP-1809581-A1 PARTICULATE MATERIAL Imerys Minerals Limited (GB) 2007-07-25 EP claimed
WO-2007010276-A1 PARTICULATE MATERIAL IMERYS MINERALS LIMITED (GB) 2007-01-25 WO claimed
EP-4700080-A2 TALC PARTICULATE ImerTech SAS (FR) 2026-02-25 EP disclosed
US-5348923-A Silica-based substrates modified by grafting of polyalkylguanidinium groups, their process of manufacture and their use as catalysts SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS - S.N.P.E. (FR) 1994-09-20 US disclosed