Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720171 | 0.88 | MTNR1A (0.57) | MTNR1AMTNR1BGRIN1GRIN2BSCN9A | |
| SCHEMBL3724569 | 0.86 | MTNR1A (0.55) | MTNR1AMTNR1BSCN9ASMN1; SMN2KDM4E | |
| SCHEMBL3716841 | 0.85 | MTNR1A (0.54) | MTNR1AMTNR1BSCN9ASMN1; SMN2KDM4E | |
| SCHEMBL3717149 | 0.84 | MTNR1A (0.58) | MTNR1AMTNR1BSCN9ASMN1; SMN2KDM4E | |
| SCHEMBL3724327 | 0.84 | MTNR1A (0.58) | MTNR1AMTNR1BSCN9ASMN1; SMN2KDM4E | |
| SCHEMBL3727674 | 0.84 | MTNR1A (0.58) | MTNR1AMTNR1BSCN9ASMN1; SMN2KDM4E | |
| SCHEMBL3727573 | 0.83 | MTNR1A (0.57) | MTNR1AMTNR1BSCN9ASMN1; SMN2KDM4E | |
| SCHEMBL3717719 | 0.82 | MTNR1A (0.58) | MTNR1AMTNR1BSCN9ASMN1; SMN2KDM4E | |
| SCHEMBL3727055 | 0.82 | ACACB (0.56) | MTNR1AMTNR1BSCN9ASMN1; SMN2KDM4E | |
| SCHEMBL3724515 | 0.82 | MTNR1A (0.58) | MTNR1AMTNR1BSCN9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |