Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 7/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 5/20 | 0.54 |
| ▸ | CA2 | P00918 | 5/20 | 0.54 |
| ▸ | CA9 | Q16790 | 5/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531795 | 1.00 | PYGB (0.70) | PYGBGAACA1CA2CA9 | |
| SCHEMBL16327600 | 0.84 | PYGB (0.75) | PYGBGAACA1CA2CA9 | |
| SCHEMBL22797044 | 0.84 | PYGB (0.75) | PYGBGAACA1CA2CA9 | |
| SCHEMBL16327599 | 0.84 | PYGB (0.75) | PYGBGAACA1CA2CA9 | |
| SCHEMBL8668587 | 0.84 | PYGB (0.74) | PYGBGAACA1CA2CA9 | |
| SCHEMBL8665848 | 0.84 | PYGB (0.74) | PYGBGAACA1CA2CA9 | |
| SCHEMBL8668278 | 0.84 | PYGB (0.74) | PYGBGAACA1CA2CA9 | |
| SCHEMBL8669655 | 0.84 | PYGB (0.74) | PYGBGAACA1CA2CA9 | |
| SCHEMBL13745906 | 0.83 | PYGB (0.77) | PYGBGAACA1CA2CA9 | |
| SCHEMBL20927544 | 0.83 | PYGB (1.00) | PYGBGAACA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8303933-B2 | Multicomponent assemblies having enhanced binding properties for diagnosis and therapy | MALLINCKRODT LLC (US) | 2012-11-06 | — | — | US | disclosed |
| US-20100280232-A1 | MULTICOMPONENT ASSEMBLIES HAVING ENHANCED BINDING PROPERTIES FOR DIAGNOSIS AND THERAPY | MALLINCKRODT INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100280177-A1 | MULTICOMPONENT ASSEMBLIES HAVING ENHANCED BINDING PROPERTIES FOR DIAGNOSIS AND THERAPY | MALLINCKRODT INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-7087212-B2 | Multicomponent assemblies having enhanced binding properties for diagnosis and therapy | MALLINCKRODT, INC (US) | 2006-08-08 | — | — | US | disclosed |
| EP-1465666-A4 | MULTICOMPONENT ASSEMBLIES HAVING ENHANCED BINDING PROPERTIES FOR DIAGNOSIS AND THERAPY | MALLINCKRODT INC (US) | 2005-11-30 | — | — | EP | disclosed |
| EP-1465666-A2 | MULTICOMPONENT ASSEMBLIES HAVING ENHANCED BINDING PROPERTIES FOR DIAGNOSIS AND THERAPY | Mallinckrodt Inc. (US) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003015606-A2 | MULTICOMPONENT ASSEMBLIES HAVING ENHANCED BINDING PROPERTIES FOR DIAGNOSIS AND THERAPY | MALLINCKRODT INC. (US) | 2003-02-27 | — | — | WO | disclosed |
| US-20030039683-A1 | Multicomponent assemblies having enhanced binding properties for diagnosis and therapy | MALLINCKRODT INC. (US) | 2003-02-27 | — | — | US | disclosed |