Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3728367 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL27545060 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL27658545 | 0.95 | — | — | |
| SCHEMBL220175 | 0.78 | — | — | |
| SCHEMBL220176 | 0.78 | — | — | |
| SCHEMBL26697685 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL31297385 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL26697668 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL26697672 | 0.76 | — | — | |
| SCHEMBL4042067 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146982-A2 | AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS | Vertex Pharmaceuticals Incorporated (US) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008128009-A2 | AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-10-23 | — | — | WO | disclosed |