⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3726641 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL27545060 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL27658545 | 0.98 | — | — | |
| SCHEMBL220175 | 0.80 | — | — | |
| SCHEMBL220176 | 0.80 | — | — | |
| SCHEMBL26697685 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL31297385 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL26697668 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL26697672 | 0.78 | — | — | |
| SCHEMBL4042067 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023208092-A1 | TRICYCLIC HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF | DANATLAS PHARMACEUTICALS CO., LTD. (CN) | 2023-11-02 | — | — | WO | disclosed |
| CN-106715430-A | Inhibition of transient receptor potential A1 ion channels | 海德拉生物科学公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-105518001-A | MODIFIED BET-PROTEIN-INHIBITING DIHYDROQUINOXALINONES AND DIHYDROPYRIDOPYRAZINONES | Bayer Pharma AG | 2016-04-20 | — | — | CN | disclosed |
| CN-103459388-B | Novel furanone derivative | CARNA BIOSCIENCES, INC. (JP) | 2015-11-25 | — | — | CN | disclosed |
| CN-103459388-A | Novel furanone derivative | SBI BIOTECH CO LTD | 2013-12-18 | — | — | CN | disclosed |
| CN-103068834-A | Phosphoramidites for reverse RNA synthesis | CHEMGENES CORP | 2013-04-24 | — | — | CN | disclosed |
| CN-102822165-A | Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same | CELGENE CORP | 2012-12-12 | — | — | CN | disclosed |
| CN-102802622-A | Compositions and methods for treating ischemia and ischemia-reperfusion injury | ISCHEMIX LLC | 2012-11-28 | — | — | CN | disclosed |
| CN-102439025-A | Rna synthesis - phosphoramidites for synthetic rna in the reverse direction, and application in convenient introduction of ligands, chromophores and modifications of synthetic rna at the 3' - end | CHEMGENES CORP | 2012-05-02 | — | — | CN | disclosed |
| CN-102421773-A | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 | BOEHRINGER INGELHEIM INT | 2012-04-18 | — | — | CN | disclosed |
| CN-101605798-A | Imidazothiazole derivative | DAIICHI SANKYO CO LTD (JP) | 2009-12-16 | — | — | CN | disclosed |
| CN-100467027-C | Combination product of inhibitor of the SRC family of non-receptor tyrosine kinases and gemcitabine | ASTRAZENECA AB (SE) | 2009-03-11 | — | — | CN | disclosed |
| WO-2008128009-A2 | AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-10-23 | — | — | WO | disclosed |
| CN-100354278-C | Quinazoline derivatives as SRC tyrosine kinase inhibitors | ASTRAZENECA AB (SE) | 2007-12-12 | — | — | CN | disclosed |
| CN-1747955-A | Nitrogen-substituted hexahydropyrazino[1,2-a]pyrimidine-4,7-dione derivatives, method for the production and use thereof as medicaments | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-03-15 | — | — | CN | disclosed |
| CN-1735617-A | Quinazoline derivatives as SRC tyrosine kinase inhibitors | ASTRAZENECA AB (SE) | 2006-02-15 | — | — | CN | disclosed |
| CN-1711094-A | Combination product of inhibitor of the SRC family of non-receptor tyrosine kinases and gemcitabine | ASTRAZENECA AB (SE) | 2005-12-21 | — | — | CN | disclosed |
| CN-1665807-A | Novel physiolgically active substances | MERCIAN CORP (JP) | 2005-09-07 | — | — | CN | disclosed |
| CN-1198825-C | 8-phenyl-6, 9-dihydro- [1,2,4] triazolo [3, 4-i ] purin-5-one derivatives | ALMIRALL PRODESFARM S A (ES) | 2005-04-27 | — | — | CN | disclosed |
| CN-1374962-A | 8-phenyl-6,9-dihydro-[1,2,4]triazolo[3,4-i] purin-5-one derivatives | ALMIRALL PRODESFARM S A (ES) | 2002-10-16 | — | — | CN | disclosed |