⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726725 | 1.00 | — | — | |
| SCHEMBL3727110 | 0.81 | EPHX2 (0.34) | — | |
| SCHEMBL22672462 | 0.79 | — | — | |
| SCHEMBL13074193 | 0.79 | — | — | |
| SCHEMBL8442210 | 0.78 | KCNH2 (0.40) | — | |
| SCHEMBL6845304 | 0.78 | KCNH2 (0.46) | — | |
| SCHEMBL22433200 | 0.78 | GNAI3 (0.43) | — | |
| SCHEMBL21322291 | 0.76 | HTT (0.37) | — | |
| SCHEMBL21290455 | 0.76 | HTT (0.37) | — | |
| SCHEMBL6843994 | 0.75 | KCNH2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825155-B2 | Oxindole derivative as feeding control agent | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-11-02 | — | — | US | disclosed |
| US-20090131398-A1 | OXINDOLE DERIVATIVE AS FEEDING CONTROL AGENT | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-05-21 | — | — | US | disclosed |
| EP-1935883-A1 | OXINDOLE DERIVATIVE AS FEEDING CONTROL AGENT | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-06-25 | — | — | EP | disclosed |