Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL372718

N.O=C(O)OC(F)(F)C(F)(F)C(F)(F)OC(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28529685 0.91
SCHEMBL31253461 0.89 THRB (0.40) THRB
SCHEMBL7062942 0.81 THRB (0.44) THRB
SCHEMBL10355830 0.76 THRB (0.36) THRB
Ammonia Solution, Strong SCHEMBL810619 0.76 THRB (0.56) THRB
Ammonia Solution, Strong SCHEMBL29802879 0.76 THRB (0.50) THRB
SCHEMBL31194778 0.76 THRB (0.39) THRB
Ammonia Solution, Strong SCHEMBL29408589 0.74 THRB (0.38) THRB
Ammonia Solution, Strong SCHEMBL29408594 0.74 THRB (0.38) THRB
SCHEMBL1766578 0.73 THRB (0.32) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9688796-B2 High melting PTFE polymers for melt-processing 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-06-27 US disclosed
US-20160039959-A1 HIGH MELTING PTFE POLYMERS FOR MELT-PROCESSING 3M INNOVATIVE PROPERTIES CO (US) 2016-02-11 US disclosed
EP-2409998-B1 High melting PTFE polymers suitable for melt-processing into shaped articles 3M INNOVATIVE PROPERTIES CO (US) 2015-11-25 EP disclosed
US-9175113-B2 High melting PFTE polymers for melt-processing 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-11-03 US disclosed
US-20130172477-A1 HIGH MELTING PTFE POLYMERS FOR MELT-PROCESSING 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-07-04 US disclosed
WO-2012012289-A1 HIGH MELTING PTFE POLYMERS FOR MELT-PROCESSING 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-01-26 WO disclosed
EP-2409998-A1 High melting PTFE polymers suitable for melt-processing into shaped articles 3M Innovative Properties Company (US) 2012-01-25 EP disclosed