Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.46 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727486 | 1.00 | DPP4 (0.46) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL13084078 | 0.80 | DPP4 (0.44) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL3927167 | 0.76 | ALDH1A1 (0.41) | LMNAMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL6461078 | 0.73 | ALDH1A1 (0.44) | LMNAMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL10012005 | 0.71 | KMT2A (0.40) | LMNAMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL14550109 | 0.71 | DPP4 (0.43) | DPP4DPP8DPP9DPP7LMNA | |
| SCHEMBL19186660 | 0.70 | DPP4 (0.48) | DPP4DPP7ALDH1A1 | |
| SCHEMBL3719922 | 0.70 | DPP4 (0.48) | DPP4DPP7ALDH1A1 | |
| SCHEMBL902826 | 0.70 | DPP4 (0.48) | DPP4DPP7ALDH1A1 | |
| SCHEMBL3721167 | 0.70 | DPP4 (0.48) | DPP4DPP7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122578-A2 | PROCESS FOR THE PREPARATION OF SITAGLIPTIN AND ITS INTERMEDIATES | MSN LABORATORIES LIMITED (IN) | 2010-10-28 | — | — | WO | disclosed |