Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 19/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3737321 | 0.87 | MRGPRX4 (0.45) | MRGPRX4 | |
| SCHEMBL9145901 | 0.84 | MRGPRX4 (0.59) | MRGPRX4 | |
| SCHEMBL11008861 | 0.84 | MRGPRX4 (0.51) | MRGPRX4 | |
| SCHEMBL11260287 | 0.83 | HTR2A (0.47) | MRGPRX4 | |
| SCHEMBL11442106 | 0.82 | AR (0.49) | MRGPRX4 | |
| SCHEMBL11436001 | 0.82 | FFAR1 (0.46) | MRGPRX4 | |
| SCHEMBL6814760 | 0.79 | PTGDR2 (0.42) | MRGPRX4 | |
| SCHEMBL10349092 | 0.78 | MRGPRX4 (0.55) | MRGPRX4 | |
| SCHEMBL12128991 | 0.78 | MRGPRX4 (0.55) | MRGPRX4 | |
| SCHEMBL9440419 | 0.78 | SLC6A2 (0.44) | MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | BOUILLOT ANNE MARIE JEANNE | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | SCD, SCD5, FADS2 | MRGPRX4 4607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.