SCHEMBL3727935

SCHEMBL3727935

NCCCC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)CN)C(=O)[C](C(=O)O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ NMT1 P30419 11/20 0.48
▸ NMT2 O60551 10/20 0.48
▸ GRIN2D O15399 1/20 0.43
▸ GRIN3B O60391 1/20 0.43
▸ GRIN1 Q05586 1/20 0.43
▸ GRIN2A Q12879 1/20 0.43
▸ GRIN2B Q13224 1/20 0.43
▸ GRIN2C Q14957 1/20 0.43
▸ GRIN3A Q8TCU5 1/20 0.43
▸ TLR2 O60603 1/20 0.43
▸ SLC15A2 Q16348 1/20 0.41
▸ FOLH1 Q04609 1/20 0.38
▸ QRFPR Q96P65 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3731630 0.87 NMT1 (0.48) NMT1NMT2GRIN2DGRIN3BGRIN1
SCHEMBL31721039 0.83 FOLH1 (0.55) NMT1NMT2GRIN2DGRIN3BGRIN1
SCHEMBL29532146 0.79 SLC15A2 (0.58) NMT1NMT2TLR2SLC15A2FOLH1
SCHEMBL30903444 0.79 TGFBR1 (0.45) NMT1NMT2GRIN2DGRIN3BGRIN1
SCHEMBL30933103 0.79 TGFBR1 (0.45) NMT1NMT2GRIN2DGRIN3BGRIN1
SCHEMBL30446798 0.79 SLC15A2 (0.55) NMT1NMT2TLR2SLC15A2FOLH1
SCHEMBL31593363 0.78 GRIN2D (0.48) NMT1NMT2GRIN2DGRIN3BGRIN1
SCHEMBL9273349 0.78 FOLH1 (0.53) NMT1NMT2GRIN2DGRIN3BGRIN1
SCHEMBL9273337 0.78 FOLH1 (0.53) NMT1NMT2GRIN2DGRIN3BGRIN1
SCHEMBL38663332 0.77 TLR2 (0.53) NMT1NMT2GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100173835-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2010-07-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100173835-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R NMT1 1060/4885NMT2 755/4885GRIN2D 3959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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