Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13044326 | 0.83 | HPGD (0.50) | LMNAGAASLC1A2SLC1A3CHRM2 | |
| Hydrochloric Acid SCHEMBL3637935 | 0.82 | LMNA (0.51) | LMNAGAASLC1A2SLC1A3CHRM2 | |
| SCHEMBL3633025 | 0.80 | AKR1C3 (0.56) | LMNAMAPTTSHRTDP1KDM4E | |
| SCHEMBL13044353 | 0.77 | LMNA (0.39) | LMNAGAASLC1A2SLC1A3CHRM2 | |
| Hydrochloric Acid SCHEMBL3637036 | 0.76 | LMNA (0.41) | LMNAGAASLC1A2SLC1A3CHRM2 | |
| SCHEMBL3635007 | 0.76 | TP53 (0.55) | LMNAGAAMAPTTP53KDM4E | |
| SCHEMBL3635128 | 0.76 | PTGS1 (0.57) | LMNAGAAMAPTTSHRTP53 | |
| SCHEMBL753845 | 0.75 | LMNA (0.69) | LMNAGAASLC1A2SLC1A3CHRM2 | |
| SCHEMBL12137582 | 0.75 | LMNA (0.69) | LMNAGAASLC1A2SLC1A3CHRM2 | |
| Benzene SCHEMBL27817325 | 0.75 | LMNA (0.69) | LMNAGAASLC1A2SLC1A3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167466-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | Glaxo Group Limited (GB) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008148853-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |