⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2249942 | 0.86 | LMNA (0.33) | — | |
| SCHEMBL2984554 | 0.86 | LMNA (0.33) | — | |
| SCHEMBL2470524 | 0.74 | — | — | |
| SCHEMBL375777 | 0.74 | — | — | |
| SCHEMBL4165018 | 0.64 | LMNA (0.42) | — | |
| SCHEMBL10774875 | 0.63 | — | — | |
| SCHEMBL18221174 | 0.63 | — | — | |
| SCHEMBL19597810 | 0.63 | — | — | |
| SCHEMBL11581971 | 0.63 | — | — | |
| SCHEMBL9643960 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046543-A1 | ACETYL DERIVATIVES OF THIAZOLES AND ANALOGUES | THE UNIVERSITY OF WOLLONGONG (AU) | 1997-12-11 | — | — | WO | claimed |
| EP-4267961-A1 | METHOD FOR DETECTING AN ANALYTE OF INTEREST IN A SAMPLE | F. Hoffmann-La Roche AG (CH) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022136234-A1 | METHOD FOR DETECTING AN ANALYTE OF INTEREST IN A SAMPLE | F. HOFFMANN-LA ROCHE AG (CH) | 2022-06-30 | — | — | WO | disclosed |
| EP-2182944-A1 | COMPOSITIONS AND METHODS FOR TREATING IMMUNOLOGICAL AND INFLAMMATORY DISEASES AND DISORDERS | Lexicon Pharmaceuticals, Inc. (US) | 2010-05-12 | — | — | EP | disclosed |
| WO-2009032972-A1 | COMPOSITIONS AND METHODS FOR TREATING IMMUNOLOGICAL AND INFLAMMATORY DISEASES AND DISORDERS | LEXICON PHARMACEUTICALS, INC. (US) | 2009-03-12 | — | — | WO | disclosed |
| WO-2000077812-A2 | LIGHT-INDUCED ELECTRON CAPTURE AT A SURFACE | NORTHEASTERN UNIVERSITY (US) | 2000-12-21 | — | — | WO | disclosed |