⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989757 | 0.85 | — | — | |
| SCHEMBL20849888 | 0.71 | — | — | |
| SCHEMBL9835682 | 0.70 | TSHR (0.31) | — | |
| SCHEMBL1708322 | 0.67 | — | — | |
| SCHEMBL28293252 | 0.67 | — | — | |
| SCHEMBL2218606 | 0.64 | — | — | |
| SCHEMBL24287629 | 0.62 | — | — | |
| SCHEMBL22692966 | 0.62 | HTR1D (0.32) | — | |
| SCHEMBL9910066 | 0.62 | — | — | |
| SCHEMBL12654575 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829568-B2 | Substituted 5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-2-ylamine compounds and their use for producing drugs | GRUENENTHAL GMBH (DE) | 2010-11-09 | — | — | US | disclosed |
| US-20080300256-A1 | Substituted 5,6,7,8-Tetrahydroimidazo[1,2-a]pyridin-2-ylamine Compounds and Their Use for Producing Drugs | GRUENENTHAL GMBH (DE) | 2008-12-04 | — | — | US | disclosed |