Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.51 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.51 |
| ▸ | CHRNG | P07510 | 1/20 | 0.51 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.51 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | CHRND | Q07001 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5615172 | 0.87 | CYP2B6 (0.56) | ERCC5FEN1SLC6A2SLC6A3CHRNA1 | |
| SCHEMBL9743797 | 0.82 | ERCC5 (0.60) | ERCC5FEN1ALDH1A1PARP1HSD11B1 | |
| SCHEMBL2542476 | 0.80 | MAPT (0.52) | ERCC5FEN1CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL634652 | 0.79 | ERCC5 (0.53) | ERCC5FEN1ALDH1A1PARP1MEN1 | |
| SCHEMBL634434 | 0.77 | ERCC5 (0.57) | ERCC5FEN1ALDH1A1SMN1; SMN2PARP1 | |
| SCHEMBL6266591 | 0.77 | ERCC5 (0.50) | ERCC5FEN1SLC6A2SLC6A3CHRNA1 | |
| SCHEMBL11791699 | 0.76 | ERCC5 (0.76) | ERCC5FEN1SMN1; SMN2PARP1MEN1 | |
| SCHEMBL29962144 | 0.76 | ERCC5 (0.76) | ERCC5FEN1SMN1; SMN2PARP1MEN1 | |
| SCHEMBL12221558 | 0.76 | ERCC5 (0.56) | ERCC5FEN1SLC6A2SLC6A3CHRNA1 | |
| SCHEMBL3317470 | 0.75 | ERCC5 (0.59) | ERCC5FEN1ALDH1A1BLMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010121022-A1 | MONOAMINE REUPTAKE INHIBITORS | RESEARCH TRIANGLE INSTITUTE (US) | 2010-10-21 | — | — | WO | disclosed |