Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.57 |
| ▸ | FEN1 | P39748 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633895 | 0.89 | ALDH1A1 (0.57) | ERCC5FEN1ALDH1A1MAPTPARP1 | |
| SCHEMBL634225 | 0.88 | ALDH1A1 (0.56) | ERCC5FEN1ALDH1A1MAPTPARP1 | |
| SCHEMBL634326 | 0.86 | ALDH1A1 (0.55) | ERCC5FEN1ALDH1A1MAPTHPGD | |
| SCHEMBL633475 | 0.86 | ALDH1A1 (0.55) | ERCC5FEN1ALDH1A1MAPTHPGD | |
| SCHEMBL29153730 | 0.86 | HSD17B3 (0.57) | ALDH1A1MAPTHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL116338 | 0.85 | ERCC5 (0.61) | ERCC5FEN1ALDH1A1MAPTPARP1 | |
| SCHEMBL634652 | 0.84 | ERCC5 (0.53) | ERCC5FEN1ALDH1A1MAPTPARP1 | |
| SCHEMBL10792354 | 0.83 | PARP1 (0.60) | ERCC5FEN1ALDH1A1PARP1SMN1; SMN2 | |
| SCHEMBL2598234 | 0.83 | ERCC5 (0.59) | ERCC5FEN1ALDH1A1MAPTPARP1 | |
| SCHEMBL3317470 | 0.83 | ERCC5 (0.59) | ERCC5FEN1ALDH1A1PARP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632892-B1 | METHOD FOR PRODUCING 3-ARYLPROPIONAMIDE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2024-07-31 | — | — | EP | disclosed |
| CN-110799490-B | 3-arylpropionamide compound and method for producing 3-arylpropionate compound | 住友化学株式会社 | 2023-05-02 | — | — | CN | disclosed |
| US-11028056-B2 | Method for producing 3-arylpropionamide compound and 3-arylpropionic acid ester compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-06-08 | — | — | US | disclosed |
| US-10919841-B2 | Monoamine reuptake inhibitors | RESEARCH TRIANGLE INSTITUTE (US) | 2021-02-16 | — | — | US | disclosed |
| US-20200165209-A1 | METHOD FOR PRODUCING 3-ARYLPROPIONAMIDE COMPOUND AND 3-ARYLPROPIONIC ACID ESTER COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-05-28 | — | — | US | disclosed |
| EP-3632892-A1 | METHOD FOR PRODUCING 3-ARYLPROPIONAMIDE COMPOUND AND 3-ARYLPROPIONIC ACID ESTER COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2020-04-08 | — | — | EP | disclosed |
| CN-110799490-A | Process for producing 3-arylpropionamide compound and process for producing 3-arylpropionate compound | 住友化学株式会社 | 2020-02-14 | — | — | CN | disclosed |
| US-20190134005-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARM INC (US) | 2019-05-09 | — | — | US | disclosed |
| US-20180215701-A1 | MONOAMINE REUPTAKE INHIBITORS | RES TRIANGLE INST (US) | 2018-08-02 | — | — | US | disclosed |
| WO-2017214505-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2017-12-14 | — | — | WO | disclosed |
| EP-0985649-B1 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES (JP) | 2004-11-24 | — | — | EP | disclosed |
| CN-1526696-A | Process for producing N- [ 1- (2, 4-dichlorophenyl) ethyl ] -2-cyano-3, 3-dimethylbutanamide | 住友化学工业株式会社 | 2004-09-08 | — | — | CN | disclosed |
| CN-1524845-A | Process for producing n-(1-(2,4-dichlorophenyl)ethyl)-2- cyano-3,3-dimethylbutanamide | 住友化学工业株式会社 | 2004-09-01 | — | — | CN | disclosed |
| CN-1153762-C | Process for producing N- [1- (2, 4-dichlorophenyl) ethyl ] -2-cyano-3, 3-dimethylbutanamide | 住友化学工业株式会社 | 2004-06-16 | — | — | CN | disclosed |
| US-6462248-B1 | THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 2002-10-08 | — | — | US | disclosed |
| EP-0985649-A2 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES, INC. (JP) | 2000-03-15 | — | — | EP | disclosed |
| EP-0579833-B1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-20 | — | — | EP | disclosed |
| CN-1131146-A | Process for producing N- [1- (2, 4-dichlorophenyl) ethyl ] -2-cyano-3, 3-dimethylbutanamide | SUMITOMO CHEMICAL CO (JP) | 1996-09-18 | — | — | CN | disclosed |
| EP-0579833-A1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY. | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992018461-A1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10919841-B2 | Monoamine reuptake inhibitors | SLC6A2, SLC6A4, SLC6A3 | ERCC5 3254/4885FEN1 3387/4885ALDH1A1 521/4885 |
| US-20180215701-A1 | MONOAMINE REUPTAKE INHIBITORS | SLC6A2, SLC6A4, SLC6A3 | ERCC5 3254/4885FEN1 3387/4885ALDH1A1 521/4885 |
| US-20200165209-A1 | METHOD FOR PRODUCING 3-ARYLPROPIONAMIDE COMPOUND AND 3-ARYLPROPIONIC ACID ESTER COMPOUND | AADAC, DDT, NAT1 | ERCC5 3789/4885FEN1 2425/4885ALDH1A1 116/4885 |
| US-11028056-B2 | Method for producing 3-arylpropionamide compound and 3-arylpropionic acid ester compound | AADAC, DDT, NAT1 | ERCC5 3789/4885FEN1 2425/4885ALDH1A1 116/4885 |
| US-20190134005-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | UGCG, MAN2B1, GBA1 | ERCC5 4023/4885FEN1 2694/4885ALDH1A1 2406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.