Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3738949 | 0.93 | CNR2 (0.65) | CNR2CNR1ALDH1A1 | |
| SCHEMBL3735283 | 0.85 | CYP1A2 (0.63) | CNR2CNR1CYP1A2ALDH1A1TSHR | |
| SCHEMBL3802259 | 0.85 | CNR2 (0.56) | CNR2CNR1ALDH1A1 | |
| SCHEMBL3742027 | 0.83 | CNR2 (0.57) | CNR2CNR1CYP1A2ALDH1A1TSHR | |
| SCHEMBL5307928 | 0.80 | CYP1A2 (0.57) | CNR2CNR1CYP1A2ALDH1A1TSHR | |
| SCHEMBL6427169 | 0.79 | MAPT (0.63) | ALDH1A1 | |
| SCHEMBL19559002 | 0.76 | MME (0.48) | ALDH1A1TSHR | |
| SCHEMBL13392839 | 0.76 | CYP1A2 (0.52) | CNR2CYP1A2ALDH1A1TSHRMTNR1A | |
| SCHEMBL4196370 | 0.74 | CYP1A2 (0.50) | CNR2CYP1A2ALDH1A1TSHRMTNR1A | |
| SCHEMBL6675601 | 0.74 | CYP1A2 (0.50) | CNR2CNR1CYP1A2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100278730-A1 | Non-Invasive Molecular Imaging of Cellular Histone Deacetylase Substrate Using Magnetic Resonance Spectroscopy (MRS) or Positron Emission Tomography (PET) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2010-11-04 | — | — | US | claimed |
| WO-2009009179-A2 | NON-INVASIVE MOLECULAR IMAGING OF CELLULAR HISTONE DEACETYLASE SUBSTRATE USING MAGNETIC RESONANCE SPECTROSCOPY (MRS) OR POSITRON EMISSION TOMOGRAPHY (PET) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-01-15 | — | — | WO | claimed |
| US-20100278730-A1 | Non-Invasive Molecular Imaging of Cellular Histone Deacetylase Substrate Using Magnetic Resonance Spectroscopy (MRS) or Positron Emission Tomography (PET) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2010-11-04 | — | — | US | disclosed |
| WO-2009009179-A2 | NON-INVASIVE MOLECULAR IMAGING OF CELLULAR HISTONE DEACETYLASE SUBSTRATE USING MAGNETIC RESONANCE SPECTROSCOPY (MRS) OR POSITRON EMISSION TOMOGRAPHY (PET) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278730-A1 | Non-Invasive Molecular Imaging of Cellular Histone Deacetylase Substrate Using Magnetic Resonance Spectroscopy (MRS) or Positron Emission Tomography (PET) | HDAC1, HDAC3, HDAC10 | CNR2 4288/4885CNR1 3978/4885CYP1A2 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.