Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | CNR2 | P34972 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307928 | 0.94 | CYP1A2 (0.57) | CYP1A2ALDH1A1CNR2TSHRSRC | |
| SCHEMBL13392839 | 0.89 | CYP1A2 (0.52) | CYP1A2ALDH1A1CNR2TSHRSRC | |
| SCHEMBL4196370 | 0.87 | CYP1A2 (0.50) | CYP1A2ALDH1A1CNR2TSHRSRC | |
| SCHEMBL6675601 | 0.87 | CYP1A2 (0.50) | CYP1A2ALDH1A1CNR2TSHRSRC | |
| SCHEMBL3742027 | 0.85 | CNR2 (0.57) | CYP1A2ALDH1A1CNR2TSHRMTNR1A | |
| SCHEMBL3729174 | 0.85 | CNR2 (0.57) | CYP1A2ALDH1A1CNR2TSHRMTNR1A | |
| SCHEMBL425361 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TSHRSRCMTNR1AMTNR1B | |
| SCHEMBL9777891 | 0.83 | CNR2 (0.59) | ALDH1A1CNR2SRCCNR1KMT2A | |
| SCHEMBL640385 | 0.82 | ACACB (0.65) | ALDH1A1POLBKMT2AHSD17B10KDM4E | |
| SCHEMBL6693251 | 0.82 | MTNR1A (0.48) | CYP1A2ALDH1A1SRCMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100278730-A1 | Non-Invasive Molecular Imaging of Cellular Histone Deacetylase Substrate Using Magnetic Resonance Spectroscopy (MRS) or Positron Emission Tomography (PET) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2010-11-04 | — | — | US | claimed |
| WO-2009009179-A2 | NON-INVASIVE MOLECULAR IMAGING OF CELLULAR HISTONE DEACETYLASE SUBSTRATE USING MAGNETIC RESONANCE SPECTROSCOPY (MRS) OR POSITRON EMISSION TOMOGRAPHY (PET) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-01-15 | — | — | WO | claimed |
| US-20100278730-A1 | Non-Invasive Molecular Imaging of Cellular Histone Deacetylase Substrate Using Magnetic Resonance Spectroscopy (MRS) or Positron Emission Tomography (PET) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2010-11-04 | — | — | US | disclosed |
| WO-2009009179-A2 | NON-INVASIVE MOLECULAR IMAGING OF CELLULAR HISTONE DEACETYLASE SUBSTRATE USING MAGNETIC RESONANCE SPECTROSCOPY (MRS) OR POSITRON EMISSION TOMOGRAPHY (PET) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-01-15 | — | — | WO | disclosed |
| US-4083868-A | INTRAOCULAR PRESSURE LOWERING AGENTS | ABBOTT LABORATORIES (US) | 1978-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278730-A1 | Non-Invasive Molecular Imaging of Cellular Histone Deacetylase Substrate Using Magnetic Resonance Spectroscopy (MRS) or Positron Emission Tomography (PET) | HDAC1, HDAC3, HDAC10 | CYP1A2 4709/4885ALDH1A1 2246/4885CNR2 4288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.