Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 9/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28436951 | 0.98 | P2RX4 (0.40) | P2RX4CYP2D6CYP2C19POLBCYP2C9 | |
| Sulfuric Acid SCHEMBL28577925 | 0.94 | P2RX4 (0.37) | P2RX4CYP2D6CYP2C19POLBCYP2C9 | |
| Phosphoric Acid SCHEMBL28440442 | 0.94 | P2RX4 (0.37) | P2RX4CYP2D6CYP2C19POLBCYP2C9 | |
| SCHEMBL28623270 | 0.86 | P2RX4 (0.45) | P2RX4CYP2C19CYP2C9KMT2ATSHR | |
| SCHEMBL7403878 | 0.85 | LMNA (0.46) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL28623368 | 0.81 | P2RX4 (0.41) | P2RX4CYP2C19CYP2C9KMT2ATSHR | |
| SCHEMBL28634028 | 0.81 | P2RX4 (0.41) | P2RX4CYP2C19CYP2C9KMT2ATSHR | |
| SCHEMBL10760089 | 0.79 | CHRM2 (0.38) | P2RX4KMT2ALMNATSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL11699063 | 0.78 | NPSR1 (0.44) | P2RX4KMT2ALMNATSHRMAPK1 | |
| SCHEMBL29128835 | 0.77 | MAPK1 (0.33) | P2RX4KMT2ALMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100278745-A1 | COMPOUNDS FOR FLUORESCENCE IMAGING | UNIVERSITE DE GENEVE (CH) | 2010-11-04 | — | — | US | disclosed |
| EP-2114462-A2 | COMPOUNDS FOR FLUORESCENCE IMAGING | UNIVERSITE DE GENEVE (CH) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008078190-A2 | COMPOUNDS FOR FLUORESCENCE IMAGING | UNIVERSITE DE GENEVE (US) | 2008-07-03 | — | — | WO | disclosed |
| EP-1250334-B1 | Medicaments useful for the treatment of proliferative diseases | LILLY CO ELI (US) | 2004-05-19 | — | — | EP | disclosed |
| EP-0664807-A1 | QUINOXALINEDIONE DERIVATIVES AS EAA ANTAGONISTS. | WARNER LAMBERT CO (US) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994009000-A1 | QUINOXALINEDIONE DERIVATIVES AS EAA ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1994-04-28 | — | — | WO | disclosed |