Limaprost

Limaprost

SCHEMBL373011

CCCC[C@H](C)C[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCC/C=C/C(=O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGIR P43119 9/20 0.59
▸ PTGER2 P43116 4/20 0.59
▸ TSHR P16473 3/20 0.59
▸ PTGER4 P35408 3/20 0.59
▸ HPGD P15428 2/20 0.59
▸ MAPK1 P28482 2/20 0.59
▸ ABCC4 O15439 2/20 0.59
▸ LMNA P02545 2/20 0.59
▸ MEN1 O00255 1/20 0.59
▸ CYP3A4 P08684 1/20 0.59
▸ KMT2A Q03164 1/20 0.59
▸ ABCC3 O15438 1/20 0.59
▸ RARB P10826 1/20 0.59
▸ RARG P13631 1/20 0.59
▸ DRD1 P21728 1/20 0.59
▸ NR4A2 P43354 1/20 0.59
▸ CYP2C19 P33261 1/20 0.59
▸ HIF1A Q16665 1/20 0.59
▸ PGR P06401 2/20 0.54
▸ NR1I2 O75469 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Limaprost SCHEMBL30532999 1.00 PTGIR (0.59) PTGIRPTGER2TSHRPTGER4HPGD
Limaprost SCHEMBL20815450 1.00 PTGIR (0.59) PTGIRPTGER2TSHRPTGER4HPGD
Limaprost SCHEMBL960148 1.00 PTGIR (0.59) PTGIRPTGER2TSHRPTGER4HPGD
Limaprost SCHEMBL23352904 1.00 PTGIR (0.59) PTGIRPTGER2TSHRPTGER4HPGD
Limaprost SCHEMBL960149 1.00 PTGIR (0.59) PTGIRPTGER2TSHRPTGER4HPGD
Limaprost SCHEMBL24342042 1.00 PTGIR (0.59) PTGIRPTGER2TSHRPTGER4HPGD
Limaprost SCHEMBL30533051 1.00 PTGIR (0.59) PTGIRPTGER2TSHRPTGER4HPGD
SCHEMBL960063 0.96 PTGIR (0.65) PTGIRPTGER2TSHRPTGER4HPGD
SCHEMBL960062 0.96 PTGIR (0.65) PTGIRPTGER2TSHRPTGER4HPGD
SCHEMBL960065 0.96 PTGIR (0.65) PTGIRPTGER2TSHRPTGER4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1539 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739302-A2 HYALURONIC ACID BASED DRUG DELIVERY SYSTEMS Cella Therapeutics, LLC (US) 2026-05-13 — — EP claimed
US-12569437-B2 Disease-site-specific liposomal formulation OSAKA UNIVERSITY (JP) 2026-03-10 — — US claimed
CN-120076792-A Liposome pharmaceutical composition and preparation method and application thereof 上海济昀生物科技有限公司 2025-05-30 — — CN claimed
CN-119947708-A Liposome and preparation method and application thereof 上海济昀生物科技有限公司 2025-05-06 — — CN claimed
EP-3895686-B1 NATURAL COMPOSITION FOR HAIR GROWTH STIMULATION AND HAIR LOSS PREVENTION AND TREATMENT FRAUNHOFER GES FORSCHUNG (DE) 2025-04-09 — — EP claimed
WO-2025010288-A2 HYALURONIC ACID BASED DRUG DELIVERY SYSTEMS VISUS THERAPEUTICS, INC. (US) 2025-01-09 — — WO claimed
CN-118894772-A Preparation method of key intermediate of high optical purity limaprost 常州博海威医药科技股份有限公司 2024-11-05 — — CN claimed
CN-118191145-A Method for determining concentration of beraprost sodium in blood plasma 丽健(广东)动物保健有限公司 2024-06-14 — — CN claimed
CN-115666532-B Sustained release preparation containing limaprost 研成精密化学株式会社 2024-06-11 — — CN claimed
CN-117959307-A Medical application of limaprost 北京泰德制药股份有限公司 2024-05-03 — — CN claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 — — WO claimed
WO-2000022909-A2 SYSTEMS FOR ORAL DELIVERY BIOTECH AUSTRALIA PTY. LIMITED (AU) 2000-04-27 — — WO claimed
EP-0989972-A1 PROSTAGLANDIN PHARMACEUTICAL COMPOSITIONS NICOX S.A. (FR) 2000-04-05 — — EP claimed
WO-1998058910-A1 PROSTAGLANDIN PHARMACEUTICAL COMPOSITIONS NICOX S.A. (FR) 1998-12-30 — — WO claimed
US-5811547-A Method for inducing crystalline state transition in medicinal substance NIPPON SHINYAJU CO., LTD. (JP) 1998-09-22 — — US claimed
WO-1998022114-A1 A METHOD FOR PROMOTING TISSUE REPAIR DUMEX-ALPHARMA A/S (DK) 1998-05-28 — — WO claimed
EP-0559911-B1 ANTITHROMBOTIC RESIN, TUBE, FILM AND COATING OTSUKA PHARMA CO LTD (JP) 1997-11-26 — — EP claimed
WO-1995006466-A1 TREATMENT OF ANORECTAL DISORDERS KOREN LABORATORIES PTY. LIMITED (AU) 1995-03-09 — — WO claimed
EP-0583482-A1 REMEDY FOR WOUND OR HEMORRHOID KAKEN PHARMACEUTICAL CO., LTD. (JP) 1994-02-23 — — EP claimed
EP-0559911-A1 ANTITHROMBOTIC RESIN, TUBE, FILM AND COATING OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1993-09-15 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569437-B2 Disease-site-specific liposomal formulation PTGER1, PLA2R1, LPAR2 PTGIR 17/4885PTGER2 7/4885TSHR 336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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