Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 9/20 | 0.59 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.59 |
| ▸ | RARB | P10826 | 1/20 | 0.59 |
| ▸ | RARG | P13631 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 2/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Limaprost SCHEMBL373011 | 1.00 | PTGIR (0.59) | PTGIRPTGER2TSHRPTGER4HPGD | |
| Limaprost SCHEMBL30532999 | 1.00 | PTGIR (0.59) | PTGIRPTGER2TSHRPTGER4HPGD | |
| Limaprost SCHEMBL960148 | 1.00 | PTGIR (0.59) | PTGIRPTGER2TSHRPTGER4HPGD | |
| Limaprost SCHEMBL23352904 | 1.00 | PTGIR (0.59) | PTGIRPTGER2TSHRPTGER4HPGD | |
| Limaprost SCHEMBL960149 | 1.00 | PTGIR (0.59) | PTGIRPTGER2TSHRPTGER4HPGD | |
| Limaprost SCHEMBL24342042 | 1.00 | PTGIR (0.59) | PTGIRPTGER2TSHRPTGER4HPGD | |
| Limaprost SCHEMBL30533051 | 1.00 | PTGIR (0.59) | PTGIRPTGER2TSHRPTGER4HPGD | |
| SCHEMBL960063 | 0.96 | PTGIR (0.65) | PTGIRPTGER2TSHRPTGER4HPGD | |
| SCHEMBL960062 | 0.96 | PTGIR (0.65) | PTGIRPTGER2TSHRPTGER4HPGD | |
| SCHEMBL960065 | 0.96 | PTGIR (0.65) | PTGIRPTGER2TSHRPTGER4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240197753-A1 | PHARMACEUTICAL COMPOSITION FOR IMPROVING CARDIAC FUNCTION | OSAKA UNIVERSITY (JP) | 2024-06-20 | — | — | US | disclosed |
| US-20240082154-A1 | DISEASE-SITE-SPECIFIC LIPOSOMAL FORMULATION | CUORIPS INC. (JP) | 2024-03-14 | — | — | US | disclosed |
| EP-4316520-A1 | PHARMACEUTICAL COMPOSITION FOR IMPROVING CARDIAC FUNCTION | OSAKA UNIVERSITY (JP) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022203070-A1 | PHARMACEUTICAL COMPOSITION FOR IMPROVING CARDIAC FUNCTION | 国立大学法人大阪大学 | 2022-09-29 | — | — | WO | disclosed |
| US-20210113464-A1 | DISEASE-SITE-SPECIFIC LIPOSOMAL FORMULATION | CUORIPS INC. (JP) | 2021-04-22 | — | — | US | disclosed |
| EP-3718537-A1 | DISEASE-SITE-SPECIFIC LIPOSOMAL FORMULATION | Osaka University (JP) | 2020-10-07 | — | — | EP | disclosed |
| US-10494338-B2 | Prostaglandin derivative | AGC Inc. (JP) | 2019-12-03 | — | — | US | disclosed |
| US-20190135743-A1 | NOVEL PROSTAGLANDIN DERIVATIVE | AGC Inc. (JP) | 2019-05-09 | — | — | US | disclosed |
| EP-3456710-A1 | NOVEL PROSTAGLANDIN DERIVATIVE | AGC INC. (JP) | 2019-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10494338-B2 | Prostaglandin derivative | PTGIR, PTGIS, PTGS1 | PTGIR 1/4885PTGER2 10/4885TSHR 4796/4885 |
| US-20190135743-A1 | NOVEL PROSTAGLANDIN DERIVATIVE | PTGIR, PTGIS, PTGER1 | PTGIR 1/4885PTGER2 9/4885TSHR 4758/4885 |
| US-20210113464-A1 | DISEASE-SITE-SPECIFIC LIPOSOMAL FORMULATION | PTGDR2, PLA2R1, PTGDR | PTGIR 7/4885PTGER2 13/4885TSHR 555/4885 |
| US-20240197753-A1 | PHARMACEUTICAL COMPOSITION FOR IMPROVING CARDIAC FUNCTION | TNNC1, FABP3, TNNT2 | PTGIR 6/4885PTGER2 10/4885TSHR 1880/4885 |
| US-20240082154-A1 | DISEASE-SITE-SPECIFIC LIPOSOMAL FORMULATION | LPAR2, PLA2R1, PTGDR2 | PTGIR 10/4885PTGER2 12/4885TSHR 664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.