Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12842002 | 0.77 | AKR1C1 (0.64) | AKR1C1HDAC4NPSR1THRBTDP1 | |
| SCHEMBL3918459 | 0.76 | AKR1C1 (0.62) | AKR1C1HDAC4NPSR1THRBTDP1 | |
| SCHEMBL2050986 | 0.73 | AKR1C1 (0.59) | AKR1C1HDAC4NPSR1THRBTDP1 | |
| SCHEMBL3737207 | 0.73 | ESR2 (0.48) | AKR1C1HDAC4NPSR1MEN1KMT2A | |
| SCHEMBL3738555 | 0.71 | AKR1C1 (0.43) | AKR1C1MEN1KMT2ACA12CA1 | |
| SCHEMBL15108974 | 0.71 | AKR1C1 (0.55) | AKR1C1HDAC4THRBTDP1MEN1 | |
| SCHEMBL27586088 | 0.69 | AKR1C1 (0.48) | AKR1C1HDAC4NPSR1MEN1KMT2A | |
| Biphenyl SCHEMBL5464808 | 0.69 | AKR1C1 (0.47) | AKR1C1NPSR1THRBTDP1SMN1; SMN2 | |
| SCHEMBL9188088 | 0.68 | AKR1C1 (0.47) | AKR1C1HDAC4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29415365 | 0.68 | ESR1 (0.44) | AKR1C1HDAC4TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7823614-B2 | Pneumatic tire | BRIDGESTONE CORPORATION (JP) | 2010-11-02 | — | — | US | disclosed |
| US-20090229728-A1 | PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| US-7491840-B2 | Compound and composition containing the same | MITSUI CHEMICALS, INC. (JP) | 2009-02-17 | — | — | US | disclosed |