Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3738555 | 0.80 | AKR1C1 (0.43) | AKR1C1CYP2D6CA12CA1CA2 | |
| SCHEMBL2302149 | 0.80 | ESR2 (0.65) | ESR2ESR1CYP3A4CA12CA1 | |
| SCHEMBL28308169 | 0.78 | ESR2 (0.67) | ESR2ESR1CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL5951161 | 0.76 | ESR1 (0.56) | ESR2ESR1AKR1C1CA12CA1 | |
| SCHEMBL9023593 | 0.75 | AKR1C1 (0.70) | ESR2ESR1AKR1C1APPCYP2C19 | |
| SCHEMBL1128270 | 0.73 | AKR1C1 (0.68) | ESR2ESR1AKR1C1APPCYP2C19 | |
| SCHEMBL3731201 | 0.73 | AKR1C1 (0.47) | AKR1C1CA12CA1CA2CA4 | |
| SCHEMBL10453123 | 0.71 | ESR2 (0.54) | ESR2ESR1CYP3A4CA12CA1 | |
| SCHEMBL11411537 | 0.71 | ESR2 (0.54) | ESR2ESR1CYP2C19CYP2C9CYP3A4 | |
| Bicarbonate SCHEMBL21142147 | 0.71 | ESR1 (0.83) | ESR2ESR1AKR1C1APPCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7823614-B2 | Pneumatic tire | BRIDGESTONE CORPORATION (JP) | 2010-11-02 | — | — | US | disclosed |
| US-20090229728-A1 | PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| US-7491840-B2 | Compound and composition containing the same | MITSUI CHEMICALS, INC. (JP) | 2009-02-17 | — | — | US | disclosed |