Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CLK1 | P49759 | 2/20 | 0.49 |
| ▸ | CLK2 | P49760 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2759646 | 0.85 | NPC1 (0.58) | NPC1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5206981 | 0.80 | MAPT (0.51) | NPC1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28172787 | 0.79 | LTA4H (0.51) | NPC1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL212750 | 0.78 | NPC1 (0.61) | NPC1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8703546 | 0.78 | AURKA (0.53) | MAPTMEN1KMT2ARAB9AKDM4E | |
| SCHEMBL28294649 | 0.78 | NPC1 (0.87) | NPC1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL16608063 | 0.76 | NPC1 (0.63) | NPC1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7452503 | 0.76 | NPC1 (0.62) | NPC1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2983473 | 0.75 | NPC1 (0.61) | NPC1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL210310 | 0.75 | NPC1 (0.61) | NPC1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9063122-B2 | Biomodulators for treatment or prevention of disease | GALLEGOS ALFREDO (MX) | 2015-06-23 | — | — | US | disclosed |
| US-20100130421-A1 | BIOMODULATORS FOR TREATMENT OR PREVENTION OF DISEASE | GALLEGOS ALFREDO | 2010-05-27 | — | — | US | disclosed |