Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.49 |
| ▸ | HTRA1 | Q92743 | 3/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732063 | 1.00 | ITGB3 (0.49) | ITGB3ITGA2BHTRA1CTSLCTSB | |
| SCHEMBL3740549 | 0.92 | ITGB3 (0.53) | ITGB3ITGA2BCTSLCTSBCTSS | |
| SCHEMBL3740546 | 0.92 | ITGB3 (0.53) | ITGB3ITGA2BCTSLCTSBCTSS | |
| SCHEMBL3733056 | 0.91 | ITGB3 (0.55) | ITGB3ITGA2BCTSLCTSBCTSS | |
| SCHEMBL3733058 | 0.91 | ITGB3 (0.55) | ITGB3ITGA2BCTSLCTSBCTSS | |
| SCHEMBL3737599 | 0.90 | ITGB3 (0.51) | ITGB3ITGA2BHTRA1CTSLCTSB | |
| SCHEMBL3737598 | 0.90 | ITGB3 (0.51) | ITGB3ITGA2BHTRA1CTSLCTSB | |
| SCHEMBL3738546 | 0.90 | ITGB3 (0.54) | ITGB3ITGA2BCTSLCTSBCTSS | |
| SCHEMBL3738543 | 0.90 | ITGB3 (0.54) | ITGB3ITGA2BCTSLCTSBCTSS | |
| SCHEMBL3748689 | 0.90 | ITGB3 (0.54) | ITGB3ITGA2BCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829737-B2 | Protein tyrosine phosphatase inhibitors and methods of use thereof | CEPTYR, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-20090131374-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CEPTYR, INC. (US) | 2009-05-21 | — | — | US | disclosed |
| US-7504389-B2 | Protein tyrosine phosphatase inhibitors and methods of use thereof | CEPTYR, INC. (US) | 2009-03-17 | — | — | US | disclosed |
| US-20080161592-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CEPTYR, INC. (US) | 2008-07-03 | — | — | US | disclosed |
| US-20060142250-A1 | Protein tyrosine phosphatase inhibitors and methods of use thereof | FALCON TECHNOLOGY PARTNERS L.P. | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161592-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | PPM1B, PTPN1, PTPN5 | ITGB3 4528/4885ITGA2B 3660/4885HTRA1 783/4885 |
| US-20060142250-A1 | Protein tyrosine phosphatase inhibitors and methods of use thereof | PPM1B, PTPN1, PTPN5 | ITGB3 4528/4885ITGA2B 3660/4885HTRA1 783/4885 |
| US-20090131374-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | PPM1B, PTPN1, PTPN5 | ITGB3 4528/4885ITGA2B 3660/4885HTRA1 783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.