SCHEMBL373244

SCHEMBL373244

O=Cc1cc(Br)c(O)c(Br)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 2/20 0.52
CYP3A4 P08684 2/20 0.50
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
TRPA1 O75762 1/20 0.50
TTR P02766 2/20 0.46
LCK P06239 2/20 0.46
PRMT1 Q99873 1/20 0.44
CISD1 Q9NZ45 1/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
PTPN2 P17706 1/20 0.42
PTPN1 P18031 1/20 0.42
PTPN6 P29350 1/20 0.42
MEN1 O00255 1/20 0.41
ALB P02768 1/20 0.41
KMT2A Q03164 1/20 0.41
KDM4E B2RXH2 1/20 0.41
PTGS2 P35354 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1005213 0.88 EGFR (0.50) ERN1TRPA1PRMT1PTPN1KDM4E
SCHEMBL29396510 0.88 EGFR (0.50) ERN1TRPA1PRMT1PTPN1KDM4E
SCHEMBL14154067 0.84 ERN1 (0.44) ERN1CYP3A4TSHRTDP1TRPA1
SCHEMBL31063495 0.84 ERN1 (0.44) ERN1CYP3A4TSHRTDP1TRPA1
SCHEMBL20607030 0.84 ERN1 (0.55) ERN1CYP3A4TSHRTDP1TRPA1
SCHEMBL28702107 0.84 CHEK1 (0.46) ERN1CYP3A4TSHRTDP1TRPA1
SCHEMBL987816 0.84 ERN1 (0.44) ERN1CYP3A4TSHRTDP1TRPA1
SCHEMBL12552996 0.84 ERN1 (0.44) ERN1CYP3A4TRPA1TTRPTPN2
SCHEMBL4756919 0.81 PTPN1 (0.69) ERN1TTRPTPN2PTPN1PTPN6
SCHEMBL5528670 0.81 KDM4E (0.46) ERN1CYP3A4LCKKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 742 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4680020-A1 COMPOSITIONS INCLUDING ALDEHYDES WITH IMPROVED RELEASE RATE AND DEGRADATION PROPERTIES FMC Agricultural Solutions A/S (DK) 2026-01-21 EP claimed
CN-119591484-A Synthesis method, product and application of vanillin and derivatives thereof 上海东庚化工技术有限公司 2025-03-11 CN claimed
CN-118807700-A Solid phase extraction membrane based on defective MOF, and preparation method and application thereof 中山大学 2024-10-22 CN claimed
WO-2024189207-A1 COMPOSITIONS INCLUDING ALDEHYDES WITH IMPROVED RELEASE RATE AND DEGRADATION PROPERTIES FMC Agricultural Solutions A/S (DK) 2024-09-19 WO claimed
CN-118043043-A Benzofuranyl hydroxy phenyl ketone derivative compound or pharmaceutically acceptable salt thereof 因诺沃治疗有限公司 2024-05-14 CN claimed
CN-114113370-B Analysis method of aromatic halogenated disinfection byproducts in water 东南大学 2024-03-26 CN claimed
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US claimed
CN-117586272-A Heterocyclic compound, preparation method and application thereof in medicine 苏州信诺维医药科技股份有限公司 2024-02-23 CN claimed
CN-115232070-B Quinolinone alkaloid derivative containing acylhydrazone group on 1-position nitrogen atom, and preparation method and application thereof 太原理工大学 2023-06-30 CN claimed
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2023-02-02 US claimed
US-20060084176-A1 Detection of uronium salts YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2006-04-20 US claimed
WO-2006029687-A1 SUBSTANCE FOR DYEING KERATINIC FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-03-23 WO claimed
WO-2006029672-A1 PRODUCTS FOR DYEING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-03-23 WO claimed
EP-1390336-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2004-02-25 EP claimed
WO-2002096849-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2002-12-05 WO claimed
EP-0488860-B1 Method for the production of polyalkoxylated aromatic compounds RHONE POULENC CHIMIE (FR) 1995-10-11 EP claimed
EP-0423010-B1 METHOD FOR THE PRODUCTION OF ALKOXYBENZALDEHYDES RHONE-POULENC CHIMIE (FR) 1993-09-29 EP claimed
EP-0193257-A1 Control of micro-organisms in water-containing compositions NIPA LABORATORIES, LTD. (GB) 1986-09-03 EP claimed
US-4218567-A Process for aromatic ethers HOFFMANN-LA ROCHE INC. (US) 1980-08-19 US claimed
US-3996291-A Process for the production of 4-hydroxy-3,5-dibromobenzaldehyde CIBA-GEIGY CORPORATION (US) 1976-12-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO ERN1 4459/4885CYP3A4 2007/4885TSHR 3526/4885
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS TYR, HAO2, HAAO ERN1 4459/4885CYP3A4 2007/4885TSHR 3526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.