SCHEMBL373289

SCHEMBL373289

C=C(C)C(=O)OC(c1ccccc1)N(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.42
LMNA P02545 1/20 0.41
ELANE P08246 1/20 0.41
ALDH1A1 P00352 3/20 0.39
CYP3A4 P08684 1/20 0.39
CHRNB2 P17787 1/20 0.38
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA4 P43681 1/20 0.38
KDM4E B2RXH2 2/20 0.37
KMT2A Q03164 1/20 0.37
EGFR P00533 2/20 0.37
KCNH2 Q12809 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
HCAR2 Q8TDS4 1/20 0.35
TSHR P16473 1/20 0.35
CYP2D6 P10635 1/20 0.34
SRC P12931 1/20 0.34
ALOX5 P09917 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28345591 0.98 HPGD (0.41) HPGDLMNAELANEALDH1A1CYP3A4
SCHEMBL5675434 0.81 HPGD (0.40) HPGDLMNAELANEALDH1A1CYP3A4
SCHEMBL1131746 0.80 ESR1 (0.49) HPGDLMNAELANEALDH1A1CYP3A4
SCHEMBL5580232 0.80 ALDH1A1 (0.45) HPGDLMNAELANEALDH1A1CYP3A4
Hydrochloric Acid SCHEMBL5247792 0.80 HPGD (0.39) HPGDLMNAELANEALDH1A1CYP3A4
SCHEMBL396062 0.79 HPGD (0.44) HPGDLMNAELANEALDH1A1CYP3A4
SCHEMBL1437800 0.79 ALDH1A1 (0.47) HPGDLMNAELANEALDH1A1CYP3A4
Hydrochloric Acid SCHEMBL1363430 0.78 ALDH1A1 (0.44) HPGDLMNAELANEALDH1A1CYP3A4
SCHEMBL28662805 0.78 HPGD (0.43) HPGDLMNAELANEALDH1A1CYP3A4
SCHEMBL10907558 0.77 HCAR2 (0.53) HPGDLMNAELANEALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6576255-B1 Injection molding method for (meth)acrylate copolymers having tertiary ammonium groups ROEHM GMBH & CO. KG (DE) 2003-06-10 US claimed
US-20250215144-A1 POLYMERIC ADHESIVE FOR ANCHORING COMPLIANT MATERIALS TO ANOTHER SURFACE CUSTOMERS BANK 2025-07-03 US disclosed
US-12139574-B2 Polymeric adhesive for anchoring compliant materials to another surface HYALEX ORTHOPAEDICS, INC. (US) 2024-11-12 US disclosed
US-20240076438-A1 POLYMERIC ADHESIVE FOR ANCHORING COMPLIANT MATERIALS TO ANOTHER SURFACE CUSTOMERS BANK 2024-03-07 US disclosed
US-11760830-B2 Polymeric adhesive for anchoring compliant materials to another surface HYALEX ORTHOPAEDICS, INC. (US) 2023-09-19 US disclosed
US-20220287345-A1 SOLUBILITY ENHANCEMENT OF POORLY SOLUBLE ACTIVES EVONIK OPERATIONS GMBH (DE) 2022-09-15 US disclosed
EP-2568967-B2 PHARMACEUTICAL COMPOSITIONS COMPRISING HYDROMORPHONE AND NALOXONE EURO CELTIQUE SA (LU) 2022-07-27 EP disclosed
EP-4009961-A1 SOLUBILITY ENHANCEMENT OF POORLY SOLUBLE ACTIVES Evonik Operations GmbH (DE) 2022-06-15 EP disclosed
US-20210332179-A1 POLYMERIC ADHESIVE FOR ANCHORING COMPLIANT MATERIALS TO ANOTHER SURFACE CUSTOMERS BANK 2021-10-28 US disclosed
CN-112898507-A Silicon block polymer surfactant and preparation method thereof 广东灵捷制造化工有限公司 2021-06-04 CN disclosed
US-20050142174-A1 Adhesive and binding agent for dermal or transdermal treatment systems ROEHM GMBH & CO. KG 2005-06-30 US disclosed
US-20050019381-A1 Binding agent which is stable in storage and used for pharmaceutical applications ROEHM GMBH & CO. KG (DE) 2005-01-27 US disclosed
US-6846891-B2 Coating and binding agent for oral or dermal pharmaceutical forms ROEHM GMBH & CO. KG (DE) 2005-01-25 US disclosed
US-20040249035-A1 Granulate or powder for producing coating or binding agents for medicaments PETEREIT HANS-ULRICH (DE) 2004-12-09 US disclosed
US-20040247687-A1 Method for production of active ingredient-containing pellets ROEHM GMBH & CO. KG (DE) 2004-12-09 US disclosed
US-20030220413-A1 Coating and binding agent for oral or dermal pharmaceutical forms ROEHM GMBH & CO. KG (DE) 2003-11-27 US disclosed
US-6624210-B1 (Meth)acrylate ester copolymer with (meth)acrylate containing tertiary amine group, plasticizer, and emulsifier; powders, pastes, aqueous suspension; encapsulation; drug delivery ROEHM GMBH & CO. KG (DE) 2003-09-23 US disclosed
US-6576255-B1 Injection molding method for (meth)acrylate copolymers having tertiary ammonium groups ROEHM GMBH & CO. KG (DE) 2003-06-10 US disclosed
US-20030064036-A1 Coating and binding agent for pharmaceutical formulations with improved storage stability ROEHM GMBH (DE) 2003-04-03 US disclosed
US-4705695-A AMMONIUM SALT OF TERTIARY AMINE SUBSTITUTED ACRYLIC POLYMER ROHM GMBH CHEMISCHE FABRIK (DE) 1987-11-10 US disclosed