Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.36 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.36 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.36 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11904863 | 0.79 | ORAI1 (0.39) | ALDH1A1KMT2AMEN1THRBHPGD | |
| SCHEMBL2143304 | 0.78 | CYP3A4 (0.38) | ALDH1A1KMT2AMEN1THRBHPGD | |
| SCHEMBL4726793 | 0.70 | TSHR (0.45) | ALDH1A1KMT2AMEN1THRBHPGD | |
| SCHEMBL15112393 | 0.70 | KDM4E (0.45) | ALDH1A1KMT2AMEN1THRBHPGD | |
| SCHEMBL2199544 | 0.70 | CYP1A2 (0.50) | ALDH1A1KMT2AMEN1THRBHPGD | |
| SCHEMBL6987582 | 0.70 | TSHR (0.52) | ALDH1A1KMT2AMEN1THRBHPGD | |
| SCHEMBL907509 | 0.70 | TSHR (0.40) | ALDH1A1KMT2AMEN1THRBHPGD | |
| SCHEMBL442587 | 0.70 | ORAI1 (0.40) | ALDH1A1KMT2AMEN1THRBHPGD | |
| SCHEMBL7796509 | 0.67 | MEN1 (0.42) | ALDH1A1KMT2AMEN1THRBHPGD | |
| SCHEMBL7376855 | 0.67 | CA4 (0.39) | ALDH1A1KMT2AMEN1THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825104-B2 | Methods and compositions for treating fungal infections | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-11-02 | — | — | US | claimed |