Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.63 |
| ▸ | ALPI | P09923 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | XIAP | P98170 | 1/20 | 0.63 |
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.55 |
| ▸ | CPA3 | P15088 | 1/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.51 |
| ▸ | GSR | P00390 | 2/20 | 0.51 |
| ▸ | GRM8 | O00222 | 1/20 | 0.51 |
| ▸ | GRM6 | O15303 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Phenylalanine SCHEMBL21002170 | 0.94 | SLC7A5 (0.71) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL1921649 | 0.93 | SLC7A5 (0.61) | SLC7A5ALPIPKMPTGS1XIAP | |
| D-Phenylalanine SCHEMBL3742888 | 0.91 | SLC7A5 (0.76) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL22500896 | 0.91 | SLC7A5 (0.76) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL1458889 | 0.91 | SLC7A5 (0.76) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL4869932 | 0.91 | SLC7A5 (0.76) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL8541118 | 0.91 | SLC7A5 (0.76) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL4771386 | 0.91 | SLC7A5 (0.76) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL23152420 | 0.90 | SLC7A5 (0.69) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL21410077 | 0.90 | SLC7A5 (0.69) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100279944-A1 | SUPPRESSION AND TREATMENT OF NEUROPATHIC PAIN | MATHISON RONALD | 2010-11-04 | — | — | US | claimed |
| EP-1998791-A1 | SUPPRESSION AND TREATMENT OF NEUROPATHIC PAIN | Salpep Biotechnology, Inc. (CA) | 2008-12-10 | — | — | EP | claimed |
| WO-2007112556-A1 | SUPPRESSION AND TREATMENT OF NEUROPATHIC PAIN | SALPEP BIOTECHNOLOGY INC. (CA) | 2007-10-11 | — | — | WO | claimed |
| US-20100279944-A1 | SUPPRESSION AND TREATMENT OF NEUROPATHIC PAIN | MATHISON RONALD | 2010-11-04 | — | — | US | disclosed |