Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3736131 | 0.77 | LRRK2 (0.35) | LRRK2CYP1A2HTR2AHTR2CHSD11B1 | |
| SCHEMBL4226263 | 0.77 | KCNH2 (0.34) | LRRK2CYP1A2HTR2AHTR2CHSD11B1 | |
| SCHEMBL3155407 | 0.77 | GAA (0.37) | LRRK2PDE2ACYP1A2HTR2AHTR2C | |
| SCHEMBL18151130 | 0.77 | GAA (0.34) | LRRK2CYP1A2HTR2AHTR2CHSD11B1 | |
| SCHEMBL4206430 | 0.74 | HTT (0.37) | KDM4EALDH1A1HTTMAPT | |
| SCHEMBL3725190 | 0.74 | HTR2A (0.36) | LRRK2CYP1A2HTR2AHTR2C | |
| SCHEMBL31445255 | 0.73 | MAPT (0.37) | KDM4ECYP1A2ALDH1A1HTTMAPT | |
| SCHEMBL17887298 | 0.71 | MAPT (0.45) | KDM4EPKMALDH1A1HTTMAPT | |
| SCHEMBL5423132 | 0.67 | HTR2A (0.36) | LRRK2CYP1A2HTR2AHTR2CHSD11B1 | |
| SCHEMBL14923156 | 0.67 | LRRK2 (0.44) | LRRK2CYP1A2ALDH1A1HTTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879878-B1 | HETEROCYCLYLETHYLHETEROCYCLYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2014-06-25 | — | — | EP | disclosed |
| EP-2518065-A1 | N-(furanylethyl)-heterocyclylcarboxamide derivatives as fungicides | Bayer CropScience AG (DE) | 2012-10-31 | — | — | EP | disclosed |
| US-7825068-B2 | Heterocyclylethylcarboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2010-11-02 | — | — | US | disclosed |
| US-20090054492-A1 | Heterocyclyethylcarboxamide Derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-02-26 | — | — | US | disclosed |
| EP-1879878-A2 | NEW HETEROCYCLYLETHYLCARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108791-A2 | HETEROCYCLYLETHYLHETEROCYCLYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054492-A1 | Heterocyclyethylcarboxamide Derivatives | CYP51A1, CYP1A2, CYP3A7 | KDM4E 823/4885PKM 546/4885LRRK2 4435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.