SCHEMBL373587

SCHEMBL373587

Cc1nccc(N)c1N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29593111 1.00
Hydrochloric Acid SCHEMBL28323289 0.97 NOS2 (0.44)
SCHEMBL580504 0.79
SCHEMBL29626655 0.79
SCHEMBL35248 0.79
SCHEMBL30374657 0.79
Hydrochloric Acid SCHEMBL28660209 0.77 NOS2 (0.62)
Hydrochloric Acid SCHEMBL9013637 0.77 NOS2 (0.44)
Hydrochloric Acid SCHEMBL7421394 0.77 NOS2 (0.44)
Ammonia Solution, Strong SCHEMBL28486618 0.77 NOS2 (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117247383-A Pharmaceutical compounds, salts thereof, formulations thereof, and methods of making and using the same 基因技术公司 2023-12-19 CN claimed
EP-3746441-A1 PHARMACEUTICAL COMPOUND, SALTS THEREOF, FORMULATIONS THEREOF, AND METHODS OF MAKING AND USING SAME GENENTECH, INC. (US) 2020-12-09 EP claimed
CN-109382137-B Preparation method and application of mesoporous Fe-Cu-SSZ-13 molecular sieve 福州大学 2020-04-10 CN claimed
CN-107955161-B Self-healing elastomer material based on reversible non-covalent bond effect and preparation method thereof 华南理工大学 2020-02-18 CN claimed
WO-2019152863-A1 PHARMACEUTICAL COMPOUND, SALTS THEREOF, FORMULATIONS THEREOF, AND METHODS OF MAKING AND USING SAME GENENTECH, INC. (US) 2019-08-08 WO claimed
CN-107955161-A A kind of self-healing elastomeric material based on the effect of reversible non-covalent key and preparation method thereof 华南理工大学 2018-04-24 CN claimed
WO-2025101780-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF OCTANT, INC. (US) 2025-05-15 WO disclosed
US-20240425448-A1 METHOD FOR PRODUCING ISOCYANATE COMPOUND, METHOD FOR PRODUCING CARBAMATE COMPOUND, METHOD FOR RECOVERING AMINE COMPOUND, AND ISOCYANATE COMPOSITION ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-12-26 US disclosed
WO-2024215070-A1 PYRAZOLOPYRIDINE DERIVATIVE COMPOUND, AND USE THEREOF 보로노이 주식회사 2024-10-17 WO disclosed
EP-4431490-A1 METHOD FOR PRODUCING ISOCYANATE COMPOUNDS, METHOD FOR PRODUCING CARBAMATE COMPOUNDS, METHOD FOR RECOVERING AMINE COMPOUNDS, AND ISOCYANATE COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2024-09-18 EP disclosed
CN-118215651-A Method for producing isocyanate compound, method for producing urethane compound, method for recovering amine compound, and isocyanate composition 旭化成株式会社 2024-06-18 CN disclosed
US-11964960-B2 Pyridinone- and pyridazinone-based compounds and uses thereof CORNELL UNIVERSITY (US) 2024-04-23 US disclosed
WO-2024044344-A1 PYRIDINYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY HOTSPOT THERAPEUTICS, INC. (US) 2024-02-29 WO disclosed
US-20060069116-A1 3-Amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes MERCK SHARP & DOHME LLC 2006-03-30 US disclosed
WO-2005044793-A2 NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-05-19 WO disclosed
US-6117893-A Heterocyclic compounds having anti-diabetic activity and their use SANKYO COMPANY, LIMITED (JP) 2000-09-12 US disclosed
US-5962470-A Heterocyclic compounds having anti-diabetic activity and their use SANKYO COMPANY, LIMITED (JP) 1999-10-05 US disclosed
US-5834501-A TREATING DIABETES OR HYPERLIPEMIA SANKYO COMPANY, LIMITED (JP) 1998-11-10 US disclosed
CN-1118781-A Heterocyclic compound with activity against diabetes and preparation and application of same MITSUTAKA CO LTD (JP) 1996-03-20 CN disclosed
US-5302601-A Useful in the treatment of diseases mediated by platelet activating factor G. D. SEARLE & CO. (US) 1994-04-12 US disclosed